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2020年6月24日,Nature杂志发表了耶鲁大学医学院Aaron Ring课题组的研究文章:IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy,研究报道肿瘤微环境中产生的 IL-18 结合蛋白(IL-18BP)可能充当分泌型免疫检查点,限制了 IL-18免疫治疗的效果,而Aaron Ring团队改造后的IL-18变体(DR-18...
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尽管抗抑郁药和心理疗法都与安慰剂效应有关58,59,但是抗抑郁药对抑郁症(尤其是轻度至中度抑郁症)的疗效仍存在争议60,61。尽管存在争议,但是一项荟萃分析表明,抗抑郁药物与心理治疗相结合比两者单独使用在焦虑症和抑郁症的治疗上更加有效62。 这是因...
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Figure 2. Total number of papers published until 13 October 2020 (from Web of Science and Scopus databases). 1.4. Scope of Discussion This survey work focuses on the single objective numerical optimization algorithms, which are the basis of the more complex optimization algorithms, such as the...
学术期刊《自然》(Nature)公布了2020年度十大科学人物和2020年度十大科学发现,中国工程院院士李兰娟、世界卫生组织总干事谭德塞、中国疾病预防控制中心传染病预防控制所研究员张永振等人入选2020十大科学人物,激活并杀死潜伏期的HIV病毒、揭秘果蝇的挑食行为、南半球臭氧层空洞恢复等入选2020世界十大科学发现。2020重大科学发现还...