遗传密码拓展技术(琥珀终止密码子抑制技术)是一种日趋成熟且易于应用的技术,目前已用于设计使用非天然氨基、亲核试剂(Nature,2019,570, 219)或光敏剂的非天然酶(图1b)。硼元素可以在蛋白质中被遗传编码为对硼苯基丙氨酸(pBoF),该非经典氨基酸(ncAA)已在蛋白质的生物偶联和生物正交标记中得到应用(Angew. Chem. I...
Nature 570, 219–223 (2019). ADS CAS PubMed Google Scholar Liu, X. et al. Genetically encoded photosensitizer protein facilitates the rational design of a miniature photocatalytic CO2-reducing enzyme. Nat. Chem. 10, 1201–1206 (2018). CAS PubMed Google Scholar Kang, F. et al. Rational...
b, The densities of outer haem, inner haem, FAD-Mg2+, GTP-Mg2+, NADPH, p47(149–158), p67(192–219), NOX2(2–7), NOX2(375–380), NOX2(409–412), NOX2(484–506), NOX2(536–541) and NOX2(567–570) are contoured at 11.77σ, 11.77σ, 16.42σ, 15.34σ, 4.16σ, 6.10σ...
[3] L. Wang,et al. Epitaxial growth of a 100-square-centimetre single-crystal hexagonal boron nitride monolayer on copper.Nature2019,570, 91-95. DOI: 10.1038/s41586-019-1226-z [4] T. A. Chen,et al. Wafer-scale single-crystal hexagonal boron nitride monolayers on Cu (111).Nature2020,...
Insulin receptor (IR) controls growth and metabolism. Insulin-like growth factor 2 (IGF2) has different binding properties on two IR isoforms, mimicking insulin’s function. However, the molecular mechanism underlying IGF2-induced IR activation remains u
Pare S, Kumar A, Bajaj V, Singh GK (2017) An efficient method for multilevel color image thresholding using cuckoo search algorithm based on minimum cross entropy. Appl Soft Comput 61:570–592 ArticleGoogle Scholar Tuba E, Alihodzic A, Tuba M (2017) Multilevel image thresholding using eleph...
74.Kim, P. Y. & Johnson, C. E.Chemotherapy-induced peripheral neuropathy: a review of recent findings. Curr.Opin. Anaesthesiol. 30,570–576 (2017). 75.Gershon, M. D. & Tack, J. Theserotonin signaling system: from basic understanding to drug development forfunctional GI disorders. Gastroe...
Faculty Opinions Recommendation of [Croft AP et al., Nature 2019 570(7760):246-251] 来自 ResearchGate 喜欢 0 阅读量: 158 作者:M Rahmati,MF Mcdermott 摘要: A number of lines of evidence obtained from high-throughput technologies, such as single-cell RNA sequencing (scRNA-seq) and ...
570 327,734 4,634 55,465 13,462 2,878 21,428 27,166 7,820 14,042 8,016 1,934 8,622 12,514 20,353 14.300 14.299 14.229 14.196 14.110 14.098 14.098 14.028 14.006 14.000 13.965 13.963 13.903 13.833 13.747 13.744 13.744 13.655 13.655 13.476 13.297 13.241 13.222 13.000 12.878 12.856 ...
2019 29.997 2020 37.461 2021 33.213 2022 34.201 2023 35.910 Total Documents 20002003200620092012201520182021090180270 Evolution of the number of published documents. All types of documents are considered, including citable and non citable documents. YearDocuments 2000 67 2001 235 2002 219 2003 214 2004...