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A theoretically promising but methodologically undeveloped way to visualize various natural bacteria in vivo with bioluminescence is to selectively deliver bioluminescent reporter into bacterial cells, directly consuming the ATP inside the bacteria. Intriguingly, the “Trojan horse” antibiotic strategy could d...
This work was supported by the Spanish Ministry of Science and Innovation (ref. PID2020-114891RB-I00) and the Comunidad de Madrid (Spain) and European funding from FSE and FEDER programs (ref. S2018/BAA-4393, AVANSECAL-II-CM). M. Guzmán-Lorite thanks the University of Alcalá for her...
thereby limiting antibody-dependent phagocytosis, which is a potential mechanism of resistance to anti-PD-1 therapies. In 2024, the FDA approved tislelizumab as monotherapy for adults with unresectable or
ScienceDirect, and Google Scholar. Various keywords were utilized, such as “natural compounds” AND “cancer” AND “PD-1” or “PD-L1”, with more specific terms like “biological products” OR “biological” AND “products” OR “biological compounds” OR “natural” AND “compounds” OR ...
inhibiting the mTOR-S6K1-S6 signaling pathway. At the same time, SFN-induced block in protein synthesis enables cells to maintain ATP at the control cells’ level (Wiczk et al.2012). Overall, SFN can promote apoptosis of tumor cells in various ways, exerting an inhibitory effect on cancer...
and risk determination3. Metabolite testing is increasingly gaining attention in animal science, including in animal genetics, animal health, and milk and meat quality4. Applications in livestock include discovery of disease biomarkers in dairy cows5,6, animal health7, growth performance8, feed effici...
2024, Journal of Lipid Research Show abstract Measuring brain docosahexaenoic acid turnover as a marker of metabolic consumption 2023, Pharmacology and Therapeutics Citation Excerpt : As proof-of-concept, Lacombe et al. and Klievik et al. showed that by feeding mice diets containing either DHA fro...
The work described in this article was supported by the National Key Research and Development Program of China (2018YFC1602300), the Research and Practice Innovation Plan for Postgraduates in Jiangsu Province (KYCX20_1840), the Natural Science Foundation of Jiangsu Province (BK20171139), the Yangtze...
Science, 326 (2009), pp. 589-592, 10.1126/science.1175602 View in ScopusGoogle Scholar Magnes and Sinner, 2016 Magnes, C., Sinner, F., 2016. Liquid Chromatography-Mass Spectrometry of Acyl-CoAs. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht, pp. 1–6. https://...