Theory shows how sexual selection can exaggerate male traits beyond naturally selected optima and also how natural selection can ultimately halt trait elaboration. Empirical evidence supports this theory, but to our knowledge, there have been no experime
A phenomenon of small-sized NPs self-assembling into a pomegranate type particle had attracted our attention. Here, we proposed a hypothesis that the size increased of T-NPs during experiment process may be due to TG effective constituent oxidative self-polymerized to form smaller size particles. ...
and toxins as they appear in the warm-dark-damp-anaerobic environment of the intestinal lumen. The system is continuously challenged because physical and chemical barriers at the epithelial interface never exclude the large antigenic load in its entirety. Furthermore, stress in the form of threatenin...
A small-molecule biosensor was developed by setting a negative correlation between the activity of TH and yellow by-product betaxanthin, which achieved high-throughput screening of TH mutants for the efficient synthesis of upstream intermediate L-DOPA and a 7.4-fold improvement of dopamine production...
of the GQDs and 3D-graphene)results in a better enrichment effect which helps produce lower detection limits.In particular,the detection limits obtained using the Ag-NPs/GQDs/3D-graphene platform can reach 10^(-11)M for rhodamine 6G,10^(-10)M for methylene blue and dopamine,and...
At the neuroanatomical level, MCHLH cell axons and MCH receptors are found brain-wide, including multiple regions speculated to be involved in object memory3,4,9,11,24, where MCH is proposed to alter synaptic plasticity thus making memories more likely to form8,9. Probing this broader ...
The weird testosterone-dopamine “link” and how to use it to BOOST your physical and sexual performance! Simple “bulking up” secret that helps you build muscle and avoid agonizing injury in the weight room! WARNING: The little-known dangers of low-T that EVERY man needs to know about be...
The proximate, or mechanistic, cause of happiness is the release of dopamine in the brain’s pleasure centers. When you eat food, you feel good. This is solely because of the dopamine receptors in your brain binding with dopamine that adjacent cells have released. The ultimate, or evolutionary...
However, selegiline is classified as a potent and irreversible inhibitor of monoamine oxidase A and B, which are critical for the degradation of dopamine, a central neurotransmitter in PD progression [27]. With respect to GAPDH, CGP 3466 (or TCH346) has a similar mechanism of action as ...
of sensitized immunotherapy. This review indicates thatFusobacterium nucleatum,Coprobacillus cateniformis,Akkermansia muciniphila,Bifidobacterium, among others, as well as intestinal microbial metabolites are closely associated with resistance to anti-tumor immunotherapy. While natural products ofpectin,inulin,...