该研究揭示了有H3K27me3和H2AK119ub1组蛋白修饰的基因能够招募蛋白复合体Rixosome到启动子区域进行Nascent RNA降解并导致转录中止,从而抑制基因的表达。 教科书描述了基因沉默是通过阻止新 RNA 的转录来介导的。在体外培养的人类细胞中发现了...
nascent rna基本解释 初生态RNA, 新生RNA 【hao86.com好工具】 临近词 nascent helix nascent action nascent nascent peptide nascent force nascent protein nascent chain nascent fibers nascent oxygen nascent strand nascent ocean手机查看nascent rna的意思,关注 好工具hao86 公众号后发送 nascent rna 即可...
因此,为了研究这些动态的重要性,研究者们就开发了多种方法来分析nascent RNA;这些方法揭示了在启动子处的差异转录程度,表明RNA聚合酶II(Pol II)在启动子附近的暂停是基因表达的关键调节步骤,证明了nascent RNA有直接调节转录的作用,并表明其序列和结构影响转录的延伸,暂停和停顿,以及发挥染色体修饰结合和增强了子的作...
First, nascent RNA is stringently purified through a combination of 4-thiouridine metabolic labeling and cellular fractionation. In contrast to cDNA or short-read–based approaches relying on reverse transcription or amplification, the sample is sequenced directly through nanopores to reveal the native ...
nascent rna发音 意思翻译 [医]初生态RNA,新生RNA 相似词语短语 nascent state───[化学]初生态;新生态 nascent states───[化学]初生态;新生态 nascent───adj.新兴的,初期的,开始存在的,发生中的 nascent recovery───新生复苏 ascendant───n.优势;星位;adj.上升的;优越的;增长的;星位的 ...
nascent RNA sequencingRNA dynamics, transcriptome‐wide profilinguridine‐to‐cytidine conversionRNA sequencing has greatly facilitated gene expression studies but is weak in studying temporal RNA dynamics; this issue can be addressed by analyzing nascent RNAs. A famous method for nascent RNA analysis is...
The programmes that direct an organism’s development and maintenance are encoded in its genome. Decoding of this information begins with regulated transcription of genomic DNA into RNA. Although transcription and its control can be tracked indirectly by
nascent RNA transcriptspre-mRNAribonucleoprotein complexesmRNA processingimmunofluorescenceconfocal microscopyin vivo cross-linkingimmunoprecipitationBiochemical methods to analyze co-transcriptional recruitment of co-activators to nascent molecules have lagged behind for many years. Most of the information on co-...
Analysis of newly transcribed, or nascent, RNA provides information that cannot be obtained from analysis using traditional total RNA preparations. The new Click-iT® Nascent RNA Capture Kit makes it simple to partition newly transcri...