Blood samples (~500 µL) were collected from rats' tails at 10, 30, 60, 120, 180, 240 and 300 min post drug administration. 2.5.2. Measurement of Tramadol Levels in Brain and Plasma The concentration of Tramadol in rat brain tissue and plasma was measured at various time points post...
During chronic lung inflammation and infection proteases such as neutrophil elastase (NE), a neutrophil-specific serine protease against P. aeruginosa, will be released into the lung lumen to fight pathogens involved in lung infections [67]. Excessive accumulation of NE in pulmonary fluids and ...