2022年5月23日,北京大学药学院天然药物及仿生药物国家重点实验室汪贻广研究员、张强教授团队在纳米领域顶级期刊Nature Nanotechnology在线发表了最新研究成果“A pyroptosis nanotuner for cancer therapy”(细胞焦亡纳米调控器用于肿瘤治疗)。 细胞焦...
Nanotechnology for cancer therapy: Invading the mechanics of cancer - ScienceDirectSignificant progress in the understanding of the (patho-)physiological principles of drug targeting to tumors has led to the identification of several important challenges posed for the use of tumor-targeted nanomedicines,...
The microbiome is emerging as a key player and driver of cancer. Traditional modalities to manipulate the microbiome (for example, antibiotics, probiotics and microbiota transplants) have been shown to improve efficacy of cancer therapies in some cases,
A pyroptosis nanotuner for cancer therapy Pyroptosis is a programmed cell death mechanism relevant in cancer therapy that can be triggered by endocytic organelle stress, but is challenging to induce in a controlled manner. In this paper the authors engineer a library of ultra-pH-sensitive nanophoto...
Thus, nanotechnology restricts the extent of the adverse effects of the anticancer therapy. Treatment for metastatic breast cancer, sarcoma in AIDS patients, ovarian and lung cancer is already on market or under final phases of many clinical trials, showing remarkable results. As nanotechnology is ...
The baffling human body and the boundless nanomaterial boon-a trap for cancer crab. Life is a balance of infinite physiochemical balanced harmonies and the basic unit cell is responsible in maintaining it. Cardiovascular diseases and Cance... S Jeelani,GSA Okan,G Anuradha,... - 《Journal of ...
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with three approved products for B-cell malignancies and a large pipeline of treatments in clinical trials. However, there are several challenges to their broad implementation. These include insufficient expansion of...
The therapeutic efficacy of reactive oxygen species (ROS) for cancer therapy is limited by the hypoxia in the tumor microenvironment and the antioxidant defense. Here, the authors address these limitations by developing a tumor microenvironment-responsive hybrid nanomedicine based on cancer associated fibr...
Nanoparticle science is also briefly addressed as the foundation upon which most nanotechnology cancer therapy is based. It is demonstrated how nanotechnology can help solve one of the most challenging and longstanding problems in medicine, which is how to eliminate cancer without harming normal body ...
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However, owing to the low radiation absorption of tumors, high doses of ionizing radiations are often needed during RT, leading to severe ...