It's definitely a medical boon for diagnosis, treatment and prevention for cancer diseases. Gold nanoparticles (AuNP's) have also been exploited for their potential application in treatment of cancer cells. No human trials have been performed yet and human trials are still at least a few years...
Zhang Y, Leonard M, Shu Y, Yang Y, Shu D, Guo P, et al. Overcoming tamoxifen resistance of human breast cancer by targeted gene silencing using multifunctional pRNA nanoparticles. ACS Nano. 2017;11(1):335–46. CASPubMedGoogle Scholar Nishikawa K, Takahashi T, Takaishi H, Miki A, Noshi...
Nanomaterials are also applied in the in vitro modeling of intestinal cancer. Three heterogeneous cell populations (epithelial colon cancer cells, human intestinal fibroblasts, and human monocytes) are used to construct 3D models of multicellular tumor spheroids. The spermine-modified dextran acetal nano...
liposomes coated with sbPA-S demonstrate noteworthy cellular uptake in the HeLa human cancer cell line, particularly when possessing a positive charge103. It is noteworthy that recent studies have demonstrated the capacity of S-layer proteins, which act as natural immunoadjuvants, to assemble on th...
In the last few years, several researchers demonstrated the potential of augmenting gene therapy with the help of nanotechnology [87, 88, 90, 115, 116] addressing a majority of these issues and successfully translated into clinical trials. 4.7 Multimodality NPs for cancer treatment Tumors are ...
In the last years, immunotherapy represents a promising strategy for treatment in cancer without massive damaging normal cells, by reprogramming and activating antitumor immunity. However, the adverse events of immunotherapy related to the low specificit
41% in advanced stages [9]. In the present work, we review the origin, risk factors, diagnosis and treatment options of ovarian cancer. Also, cancer vaccines in clinical trials, as well as perspectives of development and methods of nanotechnology-based delivery of mRNA-based vaccines are ...
Emerging nanomedicines for early cancer detection and improved treatment: Current perspective and future promise The application of nanotechnology to medicine, commonly referred to as 'nanomedicine', has the potential to transform our approach to human health and dise... DJ Bharali,SA Mousa - 《Pharma...
Nanotechnology holds immense promise in revolutionising healthcare, offering unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating infectious diseases. This review explores the multifaceted landscape of nanotechnology in healthcare while addressing the critical aspects of safety...
Arbutus Biopharma Corporation used (2015) formulated siRNA encapsulated in LNPs in the form of IV injections to target EBOV (TKM-Ebola), and it was found to be effective in the early stages of infection in macaques; however, the phase of clinical trials was withheld due to immune response ...