Kreyling, Stephanie Hirn and Carsten Schleh are at the Comprehensive Pneumology Center, Institute of Lung Biology and Disease, and Focus Network Nanoparticles and Health, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg/Munich, Germany., Wolfgang G Kreyling, S...
Direct combination of nanoparticle fabrication and exposure to lung cell cultures in a closed setup as a method to simulate accidental nanoparticle exposur... The tremendous application potential of nanosized materials stays in sharp contrast to a growing number of critical reports of their potential ...
Veranth JM, Ghandehari H, Grainger DW: Nanoparticles in the Lung. Comprehensive Toxicology 2010, 453–475.Veranth JM, Ghandehari H, Grainger DW: Nanoparticles in the Lung. In Comprehensive Toxicology. 2010:453-475.Veranth JM, Ghandehari H, Grainger DW. Nanoparticles in the Lung. ...
The expanding applications of nonviral genomic medicines in the lung remain restricted by delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen a combinatorial library of biodegradable ionizable lipids to build inhala
雷光月 木虫之王 (文坛精英) 应助: 58 (初中生) 贵宾: 0.06 金币: 122768 散金: 28630 红花: 2268 沙发: 284 帖子: 18316 在线: 2731.6小时 虫号: 1674736 注册: 2012-03-08 性别: GG 专业: 金属有机化学[资源] Nanoparticlesin the Lung书名...
lung blood vessel cells called ICAM-1 to help increase the nanoparticles' retention in the lungs. These nanoparticles were then filled with the chemokine CXCL10, creating a package the researchers named ImmunoBait. ImmunoBait particles were then attached to mouse red blood cells to create a ...
Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has different subtypes and various treatment modalities. In addition to conventional surgery, radiotherapy and chemotherapy, targeted therapy and immunotherapy have also
Background: Although adverse health effects of particulate matter with a diameter of < 100 nm (nanoparticles) have been proposed, molecular and/or experimental evidence for their facilitation of lung inflammation in vivo is not fully defined. Objective: In the present study we investigated the effec...
1g), which suggests that supermeres can cross the blood–brain barrier. Given that there was considerable uptake of supermeres in the lung and heart, we investigated related proteins in supermeres. We recently identified ACE2—the receptor for severe acute respiratory syndrome coronavirus 2 (...
Lipid nanoparticles (LNPs) for the efficient delivery of drugs need to be designed for the particular administration route and type of drug. Here we report the design of LNPs for the efficient delivery of therapeutic RNAs to the lung via nebulization. We optimized the composition, molar ratios ...