The paclitaxel protein-bound particles for injectable suspension (marketed under the brand name Abraxane®) contains nanosized complexes of paclitaxel and albumin. The molecular interaction between paclitaxel and albumin within the higher-order nanostructure is analytically challenging to assess, as is ...
antagonistic (CI > 1), or additive (CI = 1) combination.43Patients may experience significant toxicity if a multi-component combination is not carefully and accurately examined. There are sets of reference models based on different mathematical ...
This result seems to be also seen in another experiment with another two types of chemotherapeutic drugs simultaneously, paclitaxel and doxorubicin [182], loaded into magnetic chitosan nanoparticles with red blood cell membrane coating, also showed an increased duration of the drug’s circulation and ...
Its brand name is Paclitaxel, coined when it was developed commercially by Bristol-Myers Squibb; it is sold under the trademark name Taxol. Despite its clinical and commercial success, Taxol suffers from the fact that it is water insoluble. Ethanol or Cremophor EL are generally used for ...