Molecular definition of cancer specific antigens recognized by T cells opened an approach to develop cancer specific immunotherapy. Through a series of key findings in cancer immunology, for development of effective therapy major effort has been directed to how to induce T cells with fine specificity...
Chemodynamic therapyGlucose oxidaseHost-guest self-assemblyH2O2-responsiveFenton reactionAs a typical chemodynamic therapy, Fenton reaction holds great promise in cancer therapy for its effective generation of the hydroxyl radical (·OH) which induces cancer cell apoptosis. However, the tumor ...
skin cancersulphoraphaneAim: The optimization and evaluation of ethosomal nanogel (NGs) for topical delivery in skin cancer. Methods: The formulations were optimized by employing 3-factor, 3-level Box Behnken design for responses of vesicle size, and fluxes. They characterized in vitro and ...
Nanogelreceptor-mediated targetingenvironment-mediated targetingintracellular drug deliverymetastatic malignancy therapyIn Figure 1B, the description of y-axis ... J Chen,J Ding,W Xu,... - 《Nano Letters》 被引量: 0发表: 2017年 Cycloamylose‐nanogel drug delivery system‐mediated intratumor silencing...
Olaparib and Doxorubicin Co-loaded Polypeptide Nanogel for enhanced breast Cancer therapy. Front Bioeng Biotechnol. 2022;10:904344. Article PubMed PubMed Central Google Scholar Amruta A, et al. Vasculature organotropism in drug delivery. Adv Drug Deliv Rev. 2023;201:115054. Article CAS PubMed ...
More to the point, as proved in the in vivo experiments, the retention time in the vagina is prolonged and the tumor growth is effectively suppressed by the nanogel without any side effects in the orthotopic cervical cancer model. As mentioned above, this novel mucoadhesive nanogel is believed ...
The story of human dreams about curing all diseases, disorders and lesions is as old as human history. In the frontier of medical science, nanomedicine is trying to solve the problem. In this study, inspired by nanotechnology and using “grafting from”
(ALG) in conjunction with nanotherapies has emerged as a significant approach for creating biomimetic nanomedicines, which takes its cues from natural systems [45]. As a revolutionary platform, polysaccharide lading provides a simple top-down approach to building carriers with surface alterations that ...
cancer diagnosisdrug delivery systemshypoxia゛ctivated cancer therapynanogelsratiometric probesThe development of multifunctional drug delivery systems (DDSs) capable of carrying various drugs for diverse disease treatments is highly desirable yet remains challenging. Taking advantage of the excellent properties...
an additional option is required and the dOBs may be eligible as alternative cells to be used for transplantation therapy in bone diseases. A potential disadvantage of dOBs is that the dOBs are induced from fibroblasts by transducing Osterix, Oct3/4, and L-myc genes via retroviral vectors. ...