Salinomycin (Sal) has been recently discovered as a novel chemotherapeutic agent against various cancers including prostate cancer which is one of the most commonly diagnosed cancers affecting male populations worldwide. Herein we designed salinomycin nanocarrier (Sal-NPs) to extend its systemic ...
The present invention provides a magnetic nano carrier-mediated plant transgenic methods, including: the paramagnetic, magnetic nano-carrier surface covered with a layer of PEI film combining exogenous gene to construct the gene - nanometer magnetic particle carrier composite ; the gene - nano magnetic...
Among these, nanocarrier-mediated encapsulation not only increases the half-life of the peptides in vivo but also aids in the targeted delivery. Despite ... SS Rathnam,T Deepak,YJA Sahoo - 《Journal of Pharmacology & Experimental Therapeutics》 被引量: 0发表: 2024年 Efficient tumor synergistic...
For intravenously (IV) administered nanocarriers, serum albumin usually accounts for a significant fraction of the protein coating formed on the underlying nanocarrier chassis, as it is the highest concentration protein in the blood. Despite this high fractional composition within adsorbed protein layers,...
Systems pharmacological analysis of paclitaxel-mediated tumor priming that enhances nanocarrier deposition and efficacy. Mager, Systems pharmacological analysis of paclitaxel-mediated tumor priming that enhances nanocarrier deposition and efficacy, J. Pharmacol. Exp. Ther. 344 (... Sihem,Ait-Oudhia,Robert,...
The present findings suggest that PEI-PEG nanocarrier-mediated XIAP gene transfection results in XIAP expression in the cochlea, prevents damage to cochlear spiral ganglion cells, and protects hearing.Guan-gui ChenMin MaoLi-zi QiuQi-ming LiuDepartment of Otorhinolaryngologyvip中国神经再生研究(英文版)...
Nanocarrier-mediated co-delivery systems for lung cancer therapy: recent developments and prospectsPolymeric nanoparticlesLung cancerMicellesDrug delivery systemsResearch has recently focused on combinational therapy using nanocarriers to overcome the obstacles associated with conventional therapy of lung cancer. ...
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic DiseasesMicroRNAs (miRNAs) are endogenous noncoding RNAs that mediate the fibrotic process by regulating multiple targets. MicroRNA-based therapy can restore or inhibit miRNA expression and is expected to become an effective approac...
Nanocarrier-mediated co-delivery systems for lung cancer therapy: recent developments and prospectsLUNG cancerDRUG carriersCANCER treatmentNANOMEDICINENANOCARRIERSResearch has recently focused on combinational therapy using nanocarriers to overcome the obstacles associated with conventional therapy...
In this context, the morphological structure and the functions of the skin together with the potential of hair follicles in nanocarrier-mediated targeted topical skin delivery are summarized. The most frequently applied methods to examine the potential follicular penetration of drug substances via ...