Naloxegol for opioid- induced constipation in patients with noncancer pain. N Engl J Med. 2014;370:2387-2396.Chey WD, Webster L,Sostek M,et al. Naloxegol for opioid-induced constipation in patients with noncancer pain[J].New England Journal of Medicine,2014,370(25) :2387 ...
Naloxegol for Opioid-Induced Constipation in Patients with… 热度: Naloxegol (NKTR 118) 854601-70-0 GlpBio 热度: NaloxegolOxalate (Movantik ® /Moventig ® ) Researchcode:NKTR-118 1GeneralInformation Naloxegolisanopioidreceptorantagonist,whichwas ...
The US FDA has approved naloxegol (MOVANTIK) for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain, according to an AstraZeneca media release. It is expected to be available to patients in the fi... None - 《Reactions Weekly》 被引量: 0发表: 2014...
Naloxegol, an oral peripheral μ-opioid receptor antagonist, is associated with significantly increased bowel movements compared with placebo in patients with opioid-induced constipation, and it doesn't reduce opioid mediated analgesia, new research shows. The results of 2 studies "confirm the efficacy"...
naloxegol oxalate (nktr-118) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. 价格:￥电议型 号:T3355产 地:中国大陆 1共1页 在线咨询5分钟应答 想了解贵公司该产品资料和报价 提交
产品详情 Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. 储存条件: Naloxegol oxalate 相关产品 BS3 (bis(sulfosuccinimidyl)suberate) ¥918.00 Indole-3-carboxaldehyde ¥204.00 Naloxegol oxalate ...
Lepu offers Naloxegol Oxalate at resonable preices. It's therapeutic area is Opioid-induced Constipation. With the advanced technologies in the industry, our workstations can perform better in labs. Contact Lepu Medical for more information now!
产品描述Naloxegol, also known as and NKTR-118 and AZ-13337019, is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. It was approved in 2014 in adult patients with chronic, non-cancer pain. Chemically, naloxegol is a pegylated (polyethylene glycol-modified...
Naloxegol is a peripherally acting 渭-opioid receptor antagonist that was developed for the treatment of opioid-induced constipation. Modeling and simulation of naloxegol efficacy and tolerability informed selection of doses for phase III studies and provided comprehensive dosage recommendations for the ...
|1. Floettmann, E., Bui, K., Sostek, M., et al. Pharmacologic profile of naloxegol, a peripherally acting μ-opioid receptor antagonist, for the treatment of opioid-induced constipation. J. Pharmacol. Exp. Ther. 361(2), 280-291 (2017). ...