N6-methyladenosine (m6A) methylation is the most abundant RNA internal modification mainly occurring at the consensus motif DR (m6A) CH (D?=?A/G/U, R?=?A/G, H?=?A/C/U) in the 3'-UTR particularly the region near stop codons. The life cycle of m6A methylation includes "writers," ...
Breast cancer is the most common cancer type among women. Despite advanced treatment strategies, some patients still face challenges in disease control, prompting the exploration of new therapeutic approaches.N6-Methyladenosine (m6A) methylation modification regulates RNA and plays a crucial role in vario...
Research on RNA modifications, specifically N6-methyladenosine (m6A), have confirmed that they are involved in the regulation of organ I/R injury. In this review, we summarized current understanding of the regulatory roles and significance of m6A RNA methylation in I/R injury in different organs....
N6-Methyladenosine (m6A) refers to methylation of the adenosine base at the nitrogen-6 position. The existence of this modification has been known for some time. It is very common in prokaryotic genomes, but has not been found in appreciable amounts in eukaryotic DNA. It is very common howev...
N6-Methyladenosine (m6A) Rabbit Polyclonal Antibody -20℃保存,Western一抗稀释液-20℃或4℃保存,一年有效。Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。 注意事项: 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验,...
(WTAP). METTL3 is the catalytic methyltransferase subunit and METTL14 is the target recognition subunit that binds to RNA. The Virilzer/VIRMA protein directs m6A methylation to the 3’ UTRs and stop codons, and WTAP targets the complex to nuclear speckles, which are sites of RNA processing....
英文名字 N6-Methyladenosine Antibody (m6A) 供应商 Biovision 产品货号 6653-100 产品报价 ￥已停产 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868. 产品新闻 背景资料 N6-methyladenosine (m6A),or methylation of the N6 position of adenosin...
N6-methyladenosine (m6A) is methylation that occurs in the N6-position of adenosine, which is the most prevalent internal modification on eukaryotic mRNA. Accumulating evidence suggests that m6A modulates gene expression, thereby regulating cellular proc
(KSHV), the impact of m6A machinery on viral gene expression is dependent on the cell type35,36,37. In contrast, m6A negatively regulates the production of hepatitis C virus (HCV) and Zika virus38. However, the mechanism(s) by which m6A methylation regulates the virus life cycle remain ...
Epigenetic mark such as DNA methylation plays pivotal roles in regulating ripening of both climacteric and non-climacteric fruits. However, it remains unclear whether mRNA m6A methylation, which has been shown to regulate ripening of the tomato, a typica