The prevalent m6Am mRNA cap modification was recently identified as a valid target for removal by the human obesity gene FTO along with the previously established m6A mRNA modification. However, the deposition and dynamics of m6Am in regulating obesity are unknown. Here, we investigate the liver ...
DLm6Am: A Deep-Learning-Based Tool for Identifying N6,2′-O-Dimethyladenosine Sites in RNA Sequences by Zhengtao Luo 1,†, Wei Su 2,†, Liliang Lou 1, Wangren Qiu 1, Xuan Xiao 1,* and Zhaochun Xu 1,* 1 Computer Department, Jingdezhen Ceramic University, Jingdezhen 3334...
N6, 2'-O-dimethyladenosine (m6Am) is an abundant RNA methylation modification on vertebrate mRNAs and is present in the transcription initiation region of mRNAs. It has recently been experimentally shown to be associated with several human disorders, including obesity genes, and stomach cancer, amo...