N-AcylsuccinimidesDiaryl ketonesAcylative Suzuki couplingHigh atom utilizationAn acylative Suzuki coupling of activated amides with aryl boronic acids has been reported via palladium-catalyzed C-N bond cleavage. This protocol demonstrate amides can be activated by an atom-economic and cheap succinimide,...
N-Acylsuccinimides have been examined as potential acylating agents. Three different methods used to synthesize a number of these reagents are described. The rates of hydrolysis of N-acetyl, N-propionyl, N-n-butyryl, N-i-butyryl and N-n-valeryl succinimides and the rates at which they ...
117-122, " N-acylsuccinimides as acylating agents for proteins: the selective acylation of lysine residues ".H. Boyd, S.J. Leach, B. Milligan, N-acylsuccinimides as acylating agents for proteins: the selective acylation of lysine residues, Int. J. Pept. Protein Res. 4 (1972) 117 -...
N -Acylsuccinimides: twist-controlled, acyl-transfer reagents in Suzuki–Miyaura cross-coupling by N–C amide bond activation 1Yuki Osumi aChengwei Liu aMichal Szostak aLiu, C.; Szostak, M. Twisted Amides: From Obscurity to Broadly Useful Transition-Metal-Catalyzed Reactions by N-C Amide ...
N‐ACYLSUCCINIMIDES AS ACYLATING AGENTS FOR PROTEINS: SYNTHESIS, HYDROLYSIS AND AMINOLYSISdoi:10.1111/j.1399-3011.1972.tb03406.xHelen BoydI. C. CalderS. J. LeachB. MilliganBlackwell Publishing Ltd
N‐ACYLSUCCINIMIDES AS ACYLATING AGENTS FOR PROTEINS: THE SELECTIVE ACYLATION OF LYSINE RESIDUESdoi:10.1111/j.1399-3011.1972.tb03407.xHelen BoydS. J. LeachB. MilliganBlackwell Publishing Ltd
NEW MATERIAL:The N-(acylthioalkanoyloxy)succinimide of formula (X is lower alkylene; Y is lower alkyl or phenyl). EXAMPLE:N-(2-Acetylthioacetyloxy)succinimide. USE:Reagent for introducing a thiol group into the amino compound such as protein (e.g. enzyme, antibody, glycoprotein, lipoprotein,...
N-acyl succinimideN-carbamoyl succinimideA collection of N-acyl and N-carbamoyl succinimides were prepared by acylation of succinimide with acyl chlorides or by ethylene dichloride (EDC) coupling of carboxylic acids. The x-ray crystal structures of N-benzoyl and N-p-nitrobenzoyl succinimides were ...
N-acyl succinimideN-carbamoyl succinimideA collection of N-acyl and N-carbamoyl succinimides were prepared by acylation of succinimide with acyl chlorides or by ethylene dichloride (EDC) coupling of carboxylic acids. The x-ray crystal structures of N-benzoyl and N-p-nitrobenzoyl succinimides were ...
The x-ray crystal structures of N-benzoyl and N-p-nitrobenzoyl succinimides were determined. The N-acyl succinimides were effective in acylating primary amines, a secondary amine, and an aromatic amine.CassieDepartmentA.DepartmentGoodmanDepartment...