IMPORTANCE Excoriation (skin-picking) disorder (SPD) is a disabling, underrecognized condition in which individuals repeatedly pick at their skin, leading to noticeable tissue damage. To date, there has been no clearly effective pharmacologic or psychological treatment for SPD.Grant, Jon E....
N-acetylcysteine for skin picking.NAC may improve symptoms of excoriation disorder, also called skin-picking disorder (SPD). One study found that people with SPD who took 1,200-1,300 milligrams of NAC daily for 3 months reported fewer SPD behaviors than those who didn’t take the supplement...
Findings of case studies and small placebo-controlled studies suggest that NAC 600mg to 2400mg/day may ameliorate symptoms of compulsive hair pulling (trichotillomania), nail-biting and skin-picking. Subjects diagnosed with pathological gambling who responded to NAC 1800mg/day in an 8-week open-...
Evidence of N-acetylcysteine efficacy for skin picking disorder: A retrospective cohort studydoi:10.1016/j.jaad.2021.06.874Angelina S HwangElliott H CampbellJulio C Sartori-ValinottiJournal of the American Academy of Dermatology
Skin-picking disorders, trichotillomania, and nail biting are all characterized by repetitive behaviors resulting in functional deterioration and remarkable changes in physical appearance with repeated attempts to stop or decrease the behavior. While standard pharmacotherapy for obsessive-compulsive disorder ...
Promising results were found in trials testing the use of NAC, mainly as an add-on treatment, in cannabis use disorder in young people, depression in bipolar disorder, negative symptoms in schizophrenia, and excoriation (skin-picking) disorder. Despite initial optimism, recent findings regarding ...
obsessive-compulsive disordertrichotillomaniaskin pickingnail bitingglutamateN-acetylcysteineInformation on the use of N-acetylcysteine (NAC) in neuropsychiatric disorders has increased in recent publications. Although there are positive reports on the use of NAC in obsessive-compulsive and related disorders ...
In this systematic review we find favorable evidence for the use of NAC in several psychiatric and neurological disorders, particularly autism, Alzheimer's disease, cocaine and cannabis addiction, bipolar disorder, depression, trichotillomania, nail biting, skin picking, obsessive-compulsiv...