英文化学名:Sodium N-[8-(2-hydroxybenzoyl) amino] caprylate, SNAC 中文学名:沙波立沙钠 英文学名:Salcaprozate sodium 分子式:C15H20NNaO4 分子量:301.32 CAS No. : 203787-91-1 已以合作工厂名义做了药用辅料登记备案,可成吨供应大货 关键字: 8-(2-羟基苯甲酰氨基]辛酸钠;SNAC;203787-91-1;沙波...
1、snac(sodium n-[8-(2-hydroxybenzoyl)amino]caprylate),即n-(8-[2-羟基苯甲酰基]-氨基)辛酸钠,其结构式如下: 2、一种合成的两性水杨酸的n-乙酰化氨基酸衍生物,是目前最先进的肠渗透促进剂(pes),可与多肽一同粘附在胃粘膜上,从而促进药物渗透吸收,被广泛用作口服药物制剂的递送剂。 3、snac最早是由e...
中文名:N-(8-(2-hydroxybenzoyl)amino)caprylate,英文名:N-(8-(2-hydroxybenzoyl)amino)caprylate,CAS:,MSDS.
先说什么是中间体SNAC:即Sodium N-(8-[2-hydroxybenzoyl] Amino) Caprylate,8-(2-羟基苯甲酰胺基)辛酸钠,是一种氨基酸衍生物吸收促进剂,能促进肝素及人生长激素等多种蛋白质类药物溶液的口服吸收。在招股书中没有提到下游药企诺和诺德,提到了礼来等,但金凯生科8月11日在互动平台表示,公司为诺和诺德的司美格鲁...
In four cohorts of 28, 21, 19 and 29 healthy volunteers, the impact of the carrier molecule sodium N-[8-(2-hydroxybenzoyl) amino] caprylate (SNAC, CAS number: 203787-91-1) on the bioavailability of IBN was investigated. Within each cohort different oral formulations with one dose of ...
Pathway of Oral Absorption of Heparin with Sodium N-[8-(2-Hydroxybenzoyl)Amino]Caprylate PURPOSE: The oral bioavailability of heparin is negligible. Recent studies, however, have shown that sodium N-[8-(2-hydroxybenzoyl) amino]caprylate (SNAC) ... D Malkov,HZ Wang,S Dinh,... - 《Pharm ...
1-(Imidazo[1,2-a]pyridin-6-yl)propan-2-one1-(咪唑并[1,2-a]吡啶-6-基)-2-丙酮1-(咪唑并[1,2-a]吡啶-6-基)-2-丙酮116355-08-9 sodium,8-[(2-hydroxybenzoyl)amino]octanoate8-(2-羟基苯甲酰胺基)辛酸钠203787-91-1 N-Methyl-D-glucamine葡甲胺6284-40-8 ...
Keywords: notoginsenoside R1; salvianolic acids; Caco-2 cells; pharmacokinetics; sodium N-[8-(2-hydroxybenzoyl)amino]caprylate (SNAC); molecule polarity 1. Introduction There is considerable interest in delivery platforms that can improve the oral bioavailability of poorly absorbed drugs, because the ...