The synthesis and a study about the influence of the solvent in the alkylation reaction of 2-Carboxy-6-chloro-9(10H) acridone (3b) and 2-Carboxy-6-chloro-7-nitro-9(10H) acridone (3a) was done, obtaining the N-ethyl ester derivative of the alkylated products. Using the liquid-liquid ...
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*. J. Am. Chem. Soc. 2022, https://doi.org/10.1021/jacs.2c05523...
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*.J. Am. Chem. Soc.2022, https://doi.org/10.1021/jacs.2c05523
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*.J. Am. Chem. Soc.2022, https://doi.org/10.1021/j...
N-alkylation of amide, imide, and lactams in solid-liquid phase transfer catalysis using PEG-400 as catalyst in the presence of potassium hydro- xide or carbonate afforded various N-alky1ated products in good yields. This econom- ic method has the advantages of mild reaction condition and conv...
Interestingly, under these reaction conditions, the alkylation proceeds highly selective at low temperature (80 °C). Notably, in no case N,N-dialkylation was observed. In the absence of manganese catalyst, no desired product was observed (see Supplementary Table 4, entry 2). N-alkylation of ...
amine (redirected fromN-alkylation) Thesaurus Medical Encyclopedia a·mine (ə-mēn′, ăm′ēn) n. Any of a group of organic compounds of nitrogen, such as ethylamine, C2H5NH2, that may be considered ammonia derivatives in which one or more hydrogen atoms have been replaced by a hydrocar...
Neda I, Melnicky C, Vollbrecht A, Schmutzler R. An Unusual N-Alkylation Reaction During the Oxidative Addition of Hexafluoroacetone and Tetrachloro-o-benzoquinone to P-Bis(2-chloroethyl) amino-Substituted λ3P-Compounds. Synthesis, 1996, (4): 473~474...
因此 ,在催 表 2 不同反应条件对产物收率的影晌 Table2 Effectofreactionconditionsontheyieldsofproducts 3.0 4.0 3.0 4.0 3 0 4 0 3.O 4.O 3.0 4.0 3.O 4.0 3 0 4.0 3.0 4.0 3.0 4.0 3.O 4 0 3.0 4.0 10 4 0 2.0 4.0 3.0 4.0 2 0 2 O 2.O 3.0 2 0 4 0 880 催化学报 第 29卷...
ChemInform Abstract: N‐ALKYLATION OF AMINO ACID RESIDUES BY CHLOROMETHYL GROUPS. A POTENTIAL SIDE REACTION IN THE SOLID PHASE PEPTIDE SYNTHESISamino acids, peptidesDie Merrifield-Peptid-Synthesekann durch nicht veresterte Chlormethyl-Gruppen am Harz empfindlich gestrt werden.doi:10.1002/chin.197907324...