The synthesis and a study about the influence of the solvent in the alkylation reaction of 2-Carboxy-6-chloro-9(10H) acridone (3b) and 2-Carboxy-6-chloro-7-nitro-9(10H) acridone (3a) was done, obtaining the N-ethyl ester derivative of the alkylated products. Using the liquid-liquid ...
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*. J. Am. Chem. Soc. 2022, https://doi.org/10.1021/jacs.2c05523...
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*.J. Am. Chem. Soc.2022, https://doi.org/10.1021/jacs.2c05523
2) N-alkylation reaction N-烷基化反应 1. The methods for preparing these heterocyclic intermediates,including the N-alkylation reaction condition are researched. 合成了化合物1-烷基-3-取代-4-氨基吡唑-5-羧酸酯(1)和1-烷基-3-取代-5-氨基吡唑-4-羧酸酯(2),并对重要中间体3-取代-4-硝基吡唑-...
Enantioselective Reductive N-Cyclization–Alkylation Reaction of Alkene-Tethered Oxime Esters and Alkyl Iodides by Nickel Catalysis. Xue-Gong Jia, Qi-Wei Yao, Xing-Zhong Shu*.J. Am. Chem. Soc.2022, https://doi.org/10.1021/ja...
amine (redirected fromN-alkylation) Thesaurus Medical Encyclopedia a·mine (ə-mēn′, ăm′ēn) n. Any of a group of organic compounds of nitrogen, such as ethylamine, C2H5NH2, that may be considered ammonia derivatives in which one or more hydrogen atoms have been replaced by a hydrocar...
Neda I, Melnicky C, Vollbrecht A, Schmutzler R. An Unusual N-Alkylation Reaction During the Oxidative Addition of Hexafluoroacetone and Tetrachloro-o-benzoquinone to P-Bis(2-chloroethyl) amino-Substituted λ3P-Compounds. Synthesis, 1996, (4): 473~474...
ChemInform Abstract: N‐ALKYLATION OF AMINO ACID RESIDUES BY CHLOROMETHYL GROUPS. A POTENTIAL SIDE REACTION IN THE SOLID PHASE PEPTIDE SYNTHESISamino acids, peptidesDie Merrifield-Peptid-Synthesekann durch nicht veresterte Chlormethyl-Gruppen am Harz empfindlich gestrt werden.doi:10.1002/chin.197907324...
-The reaction of 3-(1-adamantyl)-4-methyl-1,2,4-triazole-5-thiol 1 with certain 2-aminoethyl chlorides in alkaline medium yielded a separable mixture of the S-(2-aminoethyl) derivatives 2 and the N-(2-aminoethyl) derivatives 3. Meanwhile, alkylation of 2-(1-adamantyl)-1,3,4-oxadiazol...
Firstly,1-chloroethyl-2-methyl imidazole was synthesized using 2-methyl imidazole and 1,2-dichloroethane as material by the reaction of N-alkylation,and th... W Duan - 《Chemical Intermediates》 被引量: 0发表: 2010年 Chemoselective N-alkylation of 2-hydroxycarbazole as a model for the synthes...