Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial. Hepatology. 2013;57(4):1542-9. doi:10.1002/hep. 26001.Squires RH, Dhawan A, Alonso E, Narkewicz MR, Shneider BL, Rodriguez-Baez N, Pediatric Acute Liver Failure ...
573 cases of acetaminophen (APAP) ingestion (277 in children under 5 years) have occurred in the Rocky Mountain Region. There were four deaths, all in the adolescent age group, prior to 1976. A multiclinic open national study of N-acetylcysteine (NAC) therapy of APAP overdose since Sept.,...
we reasoned that adjunctive therapy with an antioxidant agent,N-acetyl-L-cysteine (NAC), may provide protection from rapid neurologic decline in boys with advanced cerebral disease. We report
- 《International Journal of Pediatric Otorhinolaryngology》 被引量: 24发表: 2015年 Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors From January 1983 through August 1988, 318 consecutive patients with refractory germ cell ...
Dose-dependent skin ulcers were produced at clinically relevant MMC dose level... RT Dorr,MJ Soble,JD Liddil,... - 《Journal of Clinical Oncology Official Journal of the American Society of Clinical Oncology》 被引量: 32发表: 1986年 The Protective Effect of N‐Acetylcysteine on UVB‐Induced...
Sophie Gosselin 732Accesses Abstract -Acetylcysteine (NAC) was originally marketed in 1963 as Mucomyst® [1] for inhalation use as a mucolytic due to its ability to break disulfide bonds in mucoprotein complexes in chronic bronchopulmonary disease [2]. It was then studied as an antidote for ...
0031-3998/08/6403-0256 PEDIATRIC RESEARCH Copyright © 2008 International Pediatric Research Foundation, Inc. Vol. 64, No. 3, 2008 Printed in U.S.A. Effects of Postresuscitation N-Acetylcysteine on Cerebral Free Radical Production and Perfusion During Reoxygenation of Hypoxic Newborn Piglets TZE...
1. A dosage form for ophthalmic administration comprising (a) a therapeutically effective dose of N-acetylcysteine amide (NAC Amide), or a pharmaceutically acceptable sale or ester thereof; and (b) an ophthalmically acceptable vehicle or carrier; wherein the dosage form comprises about 25 mg to...
Droege, “Cysteine and glutathione deficiency in AIDS patients: A rationale for the treatment with N-acetylcysteine,” Pharmacology (Basel), vol. 46, No. 2, 1993, pp. 61-65. Droege et al, “Is AIDS the consequence of a virus-induced cysteine and glutathione deficiency? Chances and limitatio...
N-acetylcysteine (NAC) is a drug used widely and effectively in oral and intravenous forms as a specific antidote for acetaminophen poisoning. In children considering the toxic dose of acetaminophen ingested by the patient and the body weight, the physicia...