Drug classes:Antidotes,Mucolytics Medically reviewedby Drugs.com. Last updated on Jul 2, 2024. Uses for acetylcysteine Acetylcysteine injection is used to help prevent or lessen liver damage caused by an overdose of acetaminophen. This medicine is to be given only by or under the direct supervisi...
Acetylcysteine is a mucolytic (medicine that destroys or dissolves mucus). It is usually given by inhalation but may be given in other ways in a hospital. Acetylcysteine is used for certain lung conditions when increased amounts of mucus make breathing difficult. Acetylcysteine liquefies (thins) ...
AdultPediatric Dosage Forms & Strengths solution for inhalation (generic) 10% 20% Pulmonary Disease Facilitation of expectoration via mucolysis Solution (10 and 20%) may be used undiluted; 3-5 mL of 20% solution or 6-10 mL of 10% solution; administer 1 to 10 mL of 20% solution every ...
Since NAC has an established safety after almost 40 years of clinical use as mucolytic agent and antidote of acetaminophen toxicity, one can suggest this agent as an adjunct therapy for "testicular torsion rescue". Supplying intracellular glutathione as well as anti-oxidant and anti-inflammatory ...
Sophie Gosselin 732Accesses Abstract -Acetylcysteine (NAC) was originally marketed in 1963 as Mucomyst® [1] for inhalation use as a mucolytic due to its ability to break disulfide bonds in mucoprotein complexes in chronic bronchopulmonary disease [2]. It was then studied as an antidote for ...
AdultPediatric Dosage Forms & Strengths solution for inhalation (generic) 10% 20% Pulmonary Disease Facilitation of expectoration via mucolysis Solution (10 and 20%) may be used undiluted; 3-5 mL of 20% solution or 6-10 mL of 10% solution; administer 1 to 10 mL of 20% solution every ...
N-Acetylcysteine (NAC) is currently approved for use as a mucolytic agent in certain pulmonary disorders and as an antidote for acetaminophen overdose. Evidence thus far has shown its potential benefits in preventing VOD in patients undergoing HSCT without affecting the desired effects of conditioning...
Use of Acetylcysteine injection in pediatric patients 5 kg and greater is based on clinical practice [see Dosage and Administration (2.4)]. 10. Overdosage An initial 150 mg/kg dose of acetylcysteine for a patient weighting 106 kg was mistakenly calculated as 160 g (a decimal point error ...
First maintenance dose: Infuse over 4 hours.Second maintenance dose: Infuse over 16 hours.Oral Inhalation and Intratracheal InstillationFor use as a mucolytic agent, administer 20% acetylcysteine solution undiluted or dilute with sodium chloride injection, sodium chloride inhalation solution, sterile ...
N-acetylcysteine (NAC) is a thiol-containing antioxidant, available both as FDA-approved formulations and dietary supplements. NAC is used as a mucolytic agent in cystic fibrosis and as an antidote for acetaminophen overdose [7,8]. Because of NAC’s apparent successful clinical use in a wide ...