Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells and immature myeloid cells (IMCs) with a potent immunosuppressive activity against T-cell responses. In health, IMCs differentiate into mature granulocytes, macrophages and dendritic cells, and these IMCs...
L. Expression of cationic amino acid transporter 2 is required for myeloid-derived suppressor cell-mediated control of T cell immunity. J. Immunol. 195, 5237–5250 (2015). Article CAS PubMed Google Scholar Mairhofer, D. G. et al. Impaired gp100-Specific CD8+ T-cell responses in the ...
Myeloid-derived suppressor cells (MDSCs) are cells of neutrophil and monocyte lineages with potent immunosuppressive activity. Numerous studies in mice and humans have identified important roles for MDSCs in suppressing the antitumour response and determ
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells and immature myeloid cells (IMCs) with a potent immunosuppressive activity against T-cell responses. In health, IMCs differentiate into mature granulocytes, macrophages and dendritic cells, and these IMCs...
Myeloid-derived suppressor cells(MDSCs) are a cell population having T cell–suppressive properties. They are rarely found inhealthy adultsbut are found to be elevated in neonates (Gervassi et al., 2014). The elevated levels of MDSCs in the first few weeks of life may be a mechanism ...
骨髓抑制细胞(MDSC)分离试剂盒开发用于从淋巴组织中分离Gr-1highLy-6G+和Gr-1dimLy-6G-髓样细胞。 骨髓抑制细胞(MDSCs)是未成熟骨髓细胞的异质群体,表征为CD11b+Gr-1+,具有诱导T细胞功能障碍的能力。 它们出现在各种病理状态(癌症,感染,自身免疫疾病)中,其中未成熟骨髓祖细胞分化成粒细胞,巨噬细胞或树突细胞被部...
Myeloid-derived suppressor cells (MDSCs) are proposed to control graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the definition of human MDSCs has not yet reached consensus, and the mechanism of MDSCs to control GVHD remains unclear. ...
Clinical relevance and suppressive capacity of human myeloid-derived suppressor cell subsets. Clin. Cancer Res. 1, 24 (2018). Google Scholar Deczkowska, A., Weiner, A. & Amit, I. The physiology, pathology, and potential therapeutic applications of the TREM2 signaling pathway. Cell 181, ...
A. Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment. Cancer Immunol. Immunother. 69, 215–221 (2020). Article CAS PubMed Google Scholar Bronte, V. et al. Recommendations for myeloid-derived suppressor cell nomenclature and ...
Keywords: myeloid-derived suppressor cell (MDSC);umbilical cord blood (UCB);feto-maternal immune-tolerance;immunology;infection;autoimmunity;inflammation;immunotherapy;graft-versus-host disease (GVHD)