Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells and immature myeloid cells (IMCs) with a potent immunosuppressive activity against T-cell responses. In health, IMCs differentiate into mature granulocytes, macrophages and dendritic cells, and these IMCs...
网络骨髓衍生抑制细胞;髓系衍生抑制细胞 网络释义
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells generated during a large array of pathologic conditions ranging from cancer to obesity. These cells represent a pathologic state of activation of monocytes and relatively immature neutrophils. MDSCs are characterized by a ...
髓源性抑制细胞(myeloid-derived suppressor cells,MDSCs)是一群表型异常,具有免疫抑制功能的髓系来源细胞.在进展期肿瘤,败血症,慢性感染等病理环境中,MDSCs大量扩增... 孙健,张继明 - 《微生物与感染》 被引量: 0发表: 2022年 髓系来源抑制性细胞在多发性骨髓瘤患者中表达及临床意义 而越来越多的证据表明,一...
Myeloid-Derived Suppressor Cells Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expands during the course of inflammation, infection, and cancer.124 MDSCs include immature granulocytes, monocytes/macrophages, certain DCs, and early myeloid progenitors, and in mice...
瘤患者在免疫治疗中的受益.骨髓来源抑制细胞(Myeloid-derived suppressor cells,MDSCs)是构成肿瘤微环境和导致实体瘤免疫治疗效果不佳的主要成分之一,靶向MDSCs是改善... 陈华楠 - 郑州大学 被引量: 0发表: 2022年 小鼠骨髓间充质干细胞联合胰岛移植调节Tfh细胞及诱导免疫耐受的机制 目的 研究骨髓间充质干细胞(MSC...
Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes with potent immunosuppressive activity. They are implicated in the regulation of immune responses in many pathological conditions and are closely associated with poor clinical outcomes in cancer. Recent studies hav...
Myeloid-derived suppressor cells (MDSC) are widely implicated in immune suppression associated with tumor progression and chronic inflammation. However, very little is known about their possible role in tumor development. Here, we evaluated the role of MDSC in two experimental models of lung cancer:...
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Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. MK Srivastava,P Sinha,VK Clements,P Rodriguez,S Ostrand-... K Srivastava,P Sinha,V Clements,... 被引量: 0发表: 2010年 Abstract 424: Invasion and metastasis of human colon cancer cells is prevented...