说明:双击或选中下面任意单词,将显示该词的音标、读音、翻译等;选中中文或多个词,将显示翻译。 1) Mycophenolic acid/analogs and derivatives 霉酚酸/类似物和衍生物 2) Valine/analogs & derivatives 缬氨酸/类似物和衍生物 3) Glulamate/analogsi and ramification ...
Yang N, Wang J, Wang Z-W, Wang Q-H, Yang H-G, Wang X-J, Cheng M-S (2012) Computational insights into the inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid analogs: three-dimensional quantitative structure-activity relationship and molecular docking studies. Chem Biol ...
MMF is rapidly converted to its active form, mycophenolic acid (MPA), upon r... H U,Meier-Kriesche,L M,... - 《Therapeutic Drug Monitoring》 被引量: 205发表: 2000年 Analogs of 1,25-dihydroxyvitamin D3 as dose-reducing agents for classical immunosuppressants BACKGROUND: Most ...
Among them, compounds 1 and 2 were the first examples of mycophenolic acid analogs with a double bond at C-3′/C-4′ position. The cytotoxicity of 1-6 was evaluated against the HCT-116, BEL-7402, MGC-803, SH-SY5 Y, HO-8910 and HL-60 cell lines, and compounds 4 and 6 showed ...
Synthesis and pharmaceutical characterization of site specific mycophenolic acid-modified Xenopus glucagon-like peptide-1 analogsHanJ.SunL.Y.MaoQ.LiaoF.ZhengMEDCHEMCOMM
摘要: Stenosis, particularly restenosis associated with angioplasty or cardiac bypass operations, is treated by administering a therapeutically effective amount of mycophenolic acid, mycophenolate mofetil, or a pharmaceutically acceptable salt or derivative thereof....
liquid chromatography–tandem mass spectrometrypharmacokinetic/pharmacodynamic therapeutic drug monitoringBackground: Mycophenolic acid (MPA), a powerful inhibitor of lymphocyte proliferation, is widely used in transplantation medicine and as a glucocorticoid-sparing agent in rheumatic and inflammatory diseases. ...
Amino acid analogs were received both as methyl esters and also with the free carboxylic group. The biological activity of the products was tested on five references bacterial strains: Klebsiella pneumoniae ATCC 700603 (ESBL), Escherichia coli ATCC 8739, Pseudomonas aeruginosa ATCC 27853, ...
GLONEK T ET AL: "Full anhydrization of methylenediphosphonic acid and of phosphoric acids by a carbodiimide" INORG. CHEM. (INOCAJ);1975; VOL.14 (7); PP.1597-602, XP000907002 Univ. Illinois;Med. Cent.; Chicago; Ill. PANKIEWICZ K W ET AL: "Synthesis of methylenebis(phosphonate) analogs...
Methods: To observe the effect of mitomycin, 5-fluorouracil, leflunomide and mycophenolic acid on HBV replication and expression, we employed HepG2.2.15 and HBV-NLuc-35 cells as a cell model. Next, by native agarose gel electrophoresis (NAGE), quantitative PCR (qPCR), luciferase assay and HBV...