Brain‐derived neurotrophic factor (BDNF), the most prominent neurotrophic factor in the brain, activates mTORC1 and induces phosphorylation of its target, p70S6 kinase (p70S6K), at Thr389 in neurons. BDNF also increases mTOR‐dependent novel protein synthesis in neurons. Here we report that ...
Spinal cord transduction with an AAV1/2 vector expressing EGFP or BDNF with cMYC tag at 7 weeks after spinal cord transection.Ewelina ZiemlińskaSebastian KüglerMelitta SchachnerIwona WewiórJulita CzarkowskaBauchMałgorzata Skup