(2002) Characterization of the extended Myb-like DNA-binding domain of trithorax group protein Zeste. J. Biol. Chem., 277, 47385-47392.MOHRMANN, L., A. J. KAL and C. P. VERRIJZER, 2002 Characterization of the extended Myb-like DNA-binding domain of trithorax group protein Zeste. J ...
Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2 TRF2 is a component of shelterin, the telomere-specific protein complex that prevents DNA damage signaling and inappropriate repair at the natural ends of ......
Gel retardation assay revealed that the 115 residues on the C terminus of this protein, including the Myb motif, are sufficient for binding to the double-stranded plant telomeric sequence. The isolated DNA-binding domain of AtTRP1 recognizes each telomeric repeat centered on the sequence GGTTTAG....
MYB-like proteins contain a highly conserved DNA-binding domain, the MYB domain, which consists of approximately 50 amino acids that are folded into three α-helices. Based on the number of imperfect repeats, MYB-like proteins are divided into four groups: 1R-MYB (one repeat), 2R-MYB (two...
We have identified a rice gene encoding a DNA-binding protein that specifically recognizes the telomeric repeat sequence TTTAGGG found in plants. This gene, which we refer to as RTBP1 (rice telomere-binding protein 1), encodes a polypeptide with a predicted molecular mass of 70 kDa. RTBP1 is...
myb基因家族大多具有一个共同特征,那就是都具有高度保守的dna结合结构域-myb结构域,并因此得名。研究人员在对c-myb转录因子的研究中发现,在该类转录因子中一般具有3个保守的功能域:除了保守的dna结合结构域(dna binding domain,dbd)外,在c-端与dna结合域之间还具有一个由大量酸性氨基酸构成转录激活功能域(...
The R2R3 DNA-binding domain of Peace is similar to those of other plant MYBs regulating anthocyanin biosynthesis. Key amino acids for tertiary structure and the motif for interaction with bHLH proteins were conserved in Peace. Phylogenetic analysis indicates that Peace is closely related to AtMYB...
[23]Ogata K, Morikawa S, Nakamura H, Sekikawa A, Inoue T, et al. (1994) Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices. Cell 79: 639–648. doi: 10.1016/0092-8674(94)90549-5 ...
Blue clones indicate that there is an interaction between the protein and the DNA sequence, while a white clone indicates no interaction. For each combination and each concentration, three replicates were conducted, and one of the replicate was presented in figures. GST-pull down The N-terminal ...
LeMYBI acts as a transcriptional activator in yeast and plants, and binds to the I-box with a DNA-binding domain located in the carboxyterminal domain. 展开 关键词: Saccharomyces cerevisiae Lycopersicon esculentum DNA-Binding Proteins Proto-Oncogene Proteins c-myb Plant Proteins Transcription Factors...