Detection of the Extent of Cre-Mediated Recombination in Different Tissues of pIpC-Treated Arnt-Floxed/Mx1-Cre Mice.图片来自Mol Endocrinol. 2000 Oct;14(10):1674-81. 雌激素诱导型 Cre-ER 将雌激素受体(estrogen receptor,简称ER)的配体结合区与 Cre 重组酶相融合,形成定位于胞浆中的融合蛋白(Cre-ER...
Schneider A, Zhang Y, Guan Y, Davis LS, Breyer MD (2003) Differential, inducible gene targeting in renal epithelia, vascular endothelium, and viscera of Mx1Cre mice. Am. J. Physiol. Renal Physiol. 284: 411-417Schneider A, Zhang Y, Guan Y, Davis LS, Breyer MD. Differential, inducible...
在Mx1基因目的exons两侧分别插入loxP位点。该flox小鼠可与组织特异性Cre工具鼠交配,获得在特定细胞类型或组织中敲除Mx1基因的小鼠模型。 *使用本品系发表的文献需注明: Mx1-Flox mice (Cat. NO. 待定) were purchased from Shanghai Model Organisms Center, Inc.. 相关品系 Emx1-KO 品系名:C57BL/6Smoc-Emx...
Further, intranasal administration of Mx1-9R improved the survival of mice infected with the PR8 influenza viral strain. These data support the consideration of Mx1-9R as a novel therapeutic agent against mucosal influenza virus infection. Keywords: Mx1; influenza virus; cell-penetrating peptide;...
We have induced Pfkfb3 genomic deletion in these mice and found that it effectively decreased PFKFB3 expression and activity. To evaluate the functional consequences of Pfkfb3 deletion in vivo, we crossed Cre-bearing Pfkfb3fl/fl mice with oncogene-driven tumor models and found that Pfkfb3 ...
Spontaneous KrasG12D Activation in CFU-GM and HSCs from Mx1-Cre, KrasLSL-G12D MiceAmit, J SabnisLaurene, S CheungMonique, DailHio, Chung KangMarianne, SantaguidaMichelle, L HermistonEmmanuelle, PasseguéKevin, ShannonBenjamin, S Braun