Copy number variants typically involve DNA segments that are smaller than those recognized microscopically (<3 Mb) and larger than those recognized by direct sequencing (>1 kb). This includes so-called large-scale variants (>50 kb) that can be detected using CGH.16 There are two types of ...
Large-scale mutational analysis of EMS-induced mutation in the lacI gene of Escherichia coli. Mutat Res. 1993 Jul; 288 (1):123–131. [ PubMed ]Pienkowska,M , Glickman.B.W., Ferreira,A., Anderson.M. and Zielenska, M. (1993) Large-scale mutational analysis of EMS-induced mutation ...
Novel estimator for the change in stability upon point mutation in monomeric and multimeric proteins. - sailfish009/proteinmpnn_ddg
aquaporin 1, or the tight junction protein, claudin-1 (1:100 antibody dilutions). Protein expression is shown in WT and hydrocephalic rats at birth (P0) and P15. DAPI staining allows for visualization of nuclei.
food, and pickled vegetables. However, the incidence rates of ESCC are broadly in decline due to improved living standards in China. In Western countries, the reduction of ESCC incidence is considered primarily due to a large-scale decline in cigarette smoking6. For certain types of cancer, ...
0 × (% of cells in bin 0) + 1 × (% of cells in bin 1) + 2 × (% of cells in bin 2) + 3 × (% of cells in bin 3) + 4 × (% of cells in bin 4). H-scores will be given on a scale of 0–400. H-score = (% at...
Properties of wt and mutated Aβ assemblies.a.Representative electron microscopy images of small and large particles in Aβwtand Aβosasolution. Scale bars: 100 nm.b.Kinetics of synthetic Aβ1-42aggregation monitored by thioflavin T fluorescence in the absence and presence of Aβwtand Aβosa...
The results are shown in Figure 2 with number of evaluations on the horizontal axis at log scale, and average solution cost over 50 runs on the vertical axis. Figure 2. Results on the TSP for (a) ( 1 + 1 ) -EA, and (b) SA. Consistent with the extremely strong FDC that we ...
The promoters employed can be constitutive, or inducible, and can be used under the appropriate conditions to direct high level expression of the introduced DNA segment, such as is advantageous in the large-scale production of recombinant proteins or peptides. Appropriate promoter systems provided ...
A helix propensity scale based on experimental studies of peptides and proteins Biophys J, 75 (1998), pp. 422-427 View in ScopusGoogle Scholar 33. R. Rose, M. Weyand, M. Lammers, et al. Structural and mechanistic insights into the interaction between Rho and mammalian Dia Nature, 435 (...