The factor V Leiden mutation is a recently described autosomal dominant genetic risk factor for venous thromboembolism (VTE). Persons who are heterozygous or homozygous for this disorder are at 4 to 7 times and 50 to 100 times increased risk, respectively, for VTE. In particular, women have ...
Twitter Google Share on Facebook (redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
Synonyms for Factor V Leiden mutation in Free Thesaurus. Antonyms for Factor V Leiden mutation. 34 synonyms for mutation: anomaly, variation, deviant, freak of nature, change, variation, evolution, transformation, modification, alteration, deviation...
Factor V Leiden refers to the c.1691G>A variant in the FV gene, which encodes coagulation factor V. This variant results in resistance to factor V protein degradation by activated protein C and increases the risk of VTE 6 to 8 fold in heterozygous carriers and 80 fold in homozygous carrier...
Activated protein C resistance, caused by a point mutation factor V gene was described in last decade. This article highlights a case of a 9 year-old-boy who admitted to Ba艧kent University Hospital with right- sided hemiplegia. He was diagnosed as heterozygous for the FVL muta- tion and ...
The results of the present study showed that the incidence of blood clotting factor V Leiden mutation was found in 8 (16%) patients, from which 7 (14%) patients had heterozygous mutant and 1 (2%) had homozygous mutant for FV, the remaining patients (84%) were don't have FV Leiden (...
One patient (0路4 per cent) of the total was heterozygous for the Factor V Leiden mutation. African-American women do not appear to be at an increased risk of being heterozygous or homozygous for the Leiden mutation. This low prevalence may be confounded by ascertainment bias in a po...
Factor V Leiden mutation has emerged as one of the leading abnormalities in inherited blood coagulation disorders, resulting in a markedly increased risk f... Dorweiler,Neufang,Kasper-Koenig,... - 《Angiology》 被引量: 15发表: 2003年 Stroke in a Neonate Heterozygous for Factor V Leiden Activa...
In addition to the diagnostic criteria for APS a heterozygous factor V Leiden mutation was found in this patient, which may be a contributing risk factor... A Finis,H Ssenyonjo,U Knopp,... - 《Acta Neurochirurgica》 被引量: 7发表: 2005年 Factor V Leiden mutation in Sneddon syndrome Sned...
The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well...