Patterns of muscle strength loss with age in the general population and patients with a chronic inflammatory state. Ageing Res Rev. 2010;9:431-6.Beenakker KG, Ling CH, Meskers CG, de Craen AJ, Stijnen T, Westendorp RG, Maier AB. Patterns of muscle strength loss with age in the ...
With aging and other muscle wasting diseases, men and women undergo similar pathological changes in skeletal muscle: increased inflammation, enhanced oxidative stress, mitochondrial dysfunction, satellite cell senescence, elevated apoptosis and proteasom
Skeletal muscle aging is characterized by the loss of both muscle mass and strength, often leading to sarcopenia4. This is a major contributory factor to falls and fractures in older adults, the second-leading cause of injury and deaths5. During aging, there is a selective decrease in both t...
Skeletal muscle is greatly affected by aging, resulting in a loss of metabolic and physical function. However, the underlying molecular processes and how (lack of) physical activity is involved in age-related metabolic decline in muscle function in humans is largely unknown. Here, we compared, in...
New research from Trinity shows that age-related muscle loss, known as sarcopenia, was twice as common in adults with the most socioeconomic disadvantage (47%) compared to the least socioeconomic disadvantage (21%). Consistent evidence shows that "our muscles matter." Indeed, maintaining skeletal...
These data suggest that the muscle/bone ratio captures the intra-individual loss of muscle mass during ageing, and that the age-related loss of muscle mass may be underestimated when normalised to height squared. The quadriceps seems relatively more affected by ageing than other thigh muscles. ...
He said: 'Musclewastingis afrequentcompanionofillnessandageing. 疾病和衰老常常伴随着肌肉萎缩的发生。 www.hxen.com 3. Thoughitcouldnotclearcataractsthathadalreadyformed,itpartlyreversedmuscle-wastingandfatty-tissueloss. 虽然还无法确定白内障是否已经形成,但它反转了肌肉组织和脂肪组织的损失。
Human ageing is accompanied with deterioration in endocrine functions the most notable and well characterized of which being the decrease in the production of sex hormones. Current research literature suggests that low sex hormone concentration may be among the key mechanism for sarcopenia and muscle we...
In parallel with the progressive loss of muscle function, mitochondrial respiratory activity in human skeletal muscle has been shown to decrease with advancing age in healthy men and women13,14. Furthermore, protein levels of the mitochondrial master regulator peroxisome proliferator-activated receptor ga...
Loss of muscle strength, mass (sarcopenia), and quality (specific force) and its relationship with functional limitation and physical disability: the concord health and ageing in men project. J Am Geriatr Soc. 2010;58:2055–62. PubMed Google Scholar Sayers SP, Guralnik JM, Thombs LA, ...