Heart muscle cells in the border zone of the zebrafish heart (green), with all cell nuclei in blue. Credit: Hessel Honkoop and Fabian Kruse, ©Hubrecht Institute Researchers from the group of Jeroen Bakkers at the Hubrecht Institute (KNAW) have found that the muscle cells in the heart of...
Cells of the heart muscle cell lineage that is produced from human pluripotent stem cellsThis invention provides populations human cells of the cardiomyocyte lineage. The cells are obtained by causing cultures of pluripotent stem cells to differentiate in vitro, and then harvesting cells with certain ...
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Cachexia is associated with poor prognosis in chronic heart failure patients, but the underlying mechanisms of cachexia triggered disease progression remain poorly understood. Here, we investigate whether the dysregulation of myokine expression from wasting skeletal muscle exaggerates heart failure. RNA seque...
Muscle is a soft tissue composed of elongated cells (muscle fibres) that produce force and motion through contraction. Involuntary cardiac and smooth muscles are responsible for contraction of the heart and movement of substances through hollow organ systems, respectively, and voluntary skeletal muscles...
b. Smooth Muscle Cells Smooth muscle cells are spindle shaped and have single elongated nuclei. As in cardiac muscle cells, configuration of the nuclear membranes in smooth muscle cells changes during contraction and relaxation. Smooth muscle cells contain thin (actin) and thick (myosin) contractile...
Papadaki M, McIntire LV, Eskin SG. Effects of shear stress on growth kinetics of human aortic smooth muscle cells in vitro. Biotech Bioeng 1996; 50: 555–61. Article CAS Google Scholar Sterpetti AV et al. Shear stress modulates the proliferation rate, protein synthesis, and mitogenic acti...
Researchers have identified a new and relatively abundant pool of stem cells in the heart. The findings in the December issue of Cell Stem Cell, a Cell Press publication, show that these heart cells have the capacity for long-term expansion and can form
crustaceans) inhibitory fibres are also present. As the nerve approaches the muscle, it loses its myelin coat but remains partially covered by processes of theSchwann cells, which elsewhere surround the nerve and produce myelin. The nerve then branches several times, indenting the surface of the ...