Multiple sclerosis is an autoimmune disease in which immune cells attack and destroy the protective myelin sheaths that surround nerve fibres, leading to neurological disturbances. Latest Research and Reviews New autoimmune disorder development after immune reconstitution therapy for multiple sclerosis ...
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) with varied clinical presentations and heterogeneous histopathological features. The underlying immunological abnormalities in MS lead to various neurological and autoimmune manifestations. There is strong ...
Multiple sclerosis(MS) is anautoimmuneinflammatory disease of thecentral nervous systemthat leads to the degeneration of nerves in the brain andspinal cord. The immune or infection-fighting system in MS patients attacks the body's own cells, causing progressive damage in the brain and spinalcord. ...
Source:McGinley MP, Goldschmidt CH, Rae-Grant AD. Diagnosis and treatment of multiple sclerosis: a review.JAMA. 2021;325(8):765-779. See More About Demyelinating DisordersPatient InformationMultiple SclerosisJAMA Patient Information
Multiple sclerosis (MS) is a rare autoimmune disease that affects the central nervous system (CNS). Normally, antibodies produced by the immune system help protect the body against viruses, bacteria, and other foreign substances. In people who have MS, ...
A. MULTIPLE SCLEROSIS MULTIPLE SCLEROSIS Definition • Autoimmune, chronic inflammatory, demyelinating disease of the central nervous system; intermittent episodic neurologic impairments of varying severity caused by multiple demyelinating lesions, often of different ages • Key pathologic features: •...
The etiology of multiple sclerosis is linked to a variety of genetic and environmental factors. Both cell-mediated and humoral immune responses, triggered by extraneous or autoantigens, are likely to contribute to the pathogenesis of this disease. A greater insight into the fundamental cause of mul...
[1] Chaudhuri A, Behan PO. Multiple sclerosis: looking beyond autoimmunity.J R Soc Med. 2005 Jul;98(7):303-6.http://pmid.us/15994589. [2] Chaudhuri A, Behan PO. Multiple sclerosis is not an autoimmune disease.Arch Neurol. 2004 Oct;61(10):1610-2.http://pmid.us/15477520....
Multiple sclerosis is more common in some geographic areas (northern latitudes), and many cases show a stronggenetic predisposition. The cause or trigger of the autoimmune reaction in multiple sclerosis is not known. Viruses have been suspected as triggers (e.g., canine distemper virus), but no...
多发性硬化症(multiple sclerosis, MS)是一种原发于中枢神经系统的炎症性脱髓鞘疾病。MS确切的发病机制虽尚不清楚, 但普遍认为是在易感基因的基础上, 受环境因素触发, 由CD4+T细胞介导的中枢神经系统(central nervous system, CNS)自身免疫性疾病。实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,...