Multiple sclerosis is an autoimmune disease in which immune cells attack and destroy the protective myelin sheaths that surround nerve fibres, leading to neurological disturbances. Latest Research and Reviews Working capacity level defines the specific impairment profile of the comprehensive ICF core set ...
Multiple sclerosis(MS) is a complex disease with many different immune cells involved in its pathogenesis, and in particular T cells as the most recognized cell type. Recently, the innate immune system has also been researched for its effect on the disease. Hence, cells of the immune system ...
Despite the incomplete knowledge about the causes and pathomechanisms of multiple sclerosis (MS), activated immune cells are considered the major culprits in the initiation of the disease. A special emphasis can be put on CD4+ Tcells in MS pathogenesis, as substantial studies provide evidence for...
Our incomplete understanding of the causes and pathways involved in the onset and progression of multiple sclerosis (MS) limits our ability to effectively treat this complex neurological disease. Recent studies explore the role of immune cells at differe
Multiple sclerosis lesions have been characterized by infiltrates of T-lymphocytes, small numbers of B-lymphocytes, plasma cells and activated microglia or macrophages. Furthermore, in myelinated lesions, the expression and production of numerous related immune molecules such as cytokines, adhesion molecu...
多发性硬化症(multiple sclerosis, MS)是一种原发于中枢神经系统的炎症性脱髓鞘疾病。MS确切的发病机制虽尚不清楚, 但普遍认为是在易感基因的基础上, 受环境因素触发, 由CD4+T细胞介导的中枢神经系统(central nervous system, CNS)自身免疫性疾病。实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,...
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system with an autoimmune attack on the components of the myelin sheath and axons. The etiology of the disease remains largely unknown, but it is commonly acknowledged that the development of MS probably results...
Multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system (CNS), is currently regarded as an organ-specific, T-cell-mediated autoimmune disease. Although the immunopathogenesis of MS is largely hypothetical and several immune-mediated processes may account for ...
This review of the literature on mast cells (MC) suggests that when activated they may play a central role in disease syndromes with a neural, immune and e... TC Theoharides - 《International Journal of Tissue Reactions》 被引量: 456发表: 1996年 Respiratory Function in Multiple Sclerosis: ...
multiple sclerosis (ms) is the most common acquired inflammatory demyelinating disease of the central nervous system in humans. a histopathological hallmark of early ms is the presence of inflammatory cellular infiltrates in actively demyelinating lesions. most of these cells are macrophages that arise ...