Crunkhorn S. Autoimmune disease: SIRT1 inhibition suppresses multiple sclerosis. Nat Rev Drug Discov. 2015; 14(7):460. PMID: 26129800CRUNKHORN S.Autoimmune disease:SIRT1 inhibition suppresses multiple sclerosis.Nat Rev Drug Discov.2015.460-
Multiple Sclerosis Multiple sclerosis is an autoimmune disease in which T cells attack oligodendroglial cells in the CNS causing demyelination of neurons and failure of normal axonal conduction. Multiple sclerosis tends to be a relapsing and remitting disease in which localized areas in the brain are...
Free Essay: MULTIPLE SCLEROSIS 2 Abstract Multiple sclerosis is an autoimmune disease that affects thousands of people worldwide. No one really knows what...
Multiple sclerosis (MS) is a rare autoimmune disease that affects the central nervous system (CNS). Normally, antibodies produced by the immune system help protect the body against viruses, bacteria, and other foreign substances. In people who have MS, ...
Multiple sclerosis (MS) is a chronic autoimmune disease that damages the protective covering around nerves in the brain and spinal cord due to inflammation. In areas of the brain and spinal cord affected by MS, signals transmitted across nerves are slowed or blocked, causing neurological symp...
Multiple sclerosis (MS) is the commonest disease of the central nervous system (CNS) to cause permanent disability in young adults. Based on strong circumstantial evidence, MS is considered to be an organ-specific autoimmune disorder, but the exact cause is as yet unknown. It appears that the...
A. MULTIPLE SCLEROSIS MULTIPLE SCLEROSIS Definition • Autoimmune, chronic inflammatory, demyelinating disease of the central nervous system; intermittent episodic neurologic impairments of varying severity caused by multiple demyelinating lesions, often of different ages • Key pathologic features: •...
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that causes demyelination, axonal degeneration and astrogliosis, resulting in progressive neurological disability. Fuelled by an evolving understanding of MS immunopathogenesis, the range of available immunotherapies for clinic...
多发性硬化症(multiple sclerosis, MS)是一种原发于中枢神经系统的炎症性脱髓鞘疾病。MS确切的发病机制虽尚不清楚, 但普遍认为是在易感基因的基础上, 受环境因素触发, 由CD4+T细胞介导的中枢神经系统(central nervous system, CNS)自身免疫性疾病。实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,...
Multiple sclerosis (MS) is believed to be an autoimmune disease in which autoreactive T cells infiltrate the central nervous system (CNS). Animal models of... T Brabb,PV Dassow,N Ordonez,... - 《Journal of Experimental Medicine》 被引量: 505发表: 2000年 Vaccination and autoimmunity-'vaccin...