The meaning of MULTIPLE MYELOMA is a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body.
Recent insights into the biological basis of myeloma have resulted in several new drugs becoming available. Thalidomide, bortezomib and lenalidomide have each improved the response to therapy, but they are expensive. Future challenges include optimising the sequence of these drugs, refining their ...
New drugs in multiple myeloma. Curr. Opin. Support. Palliat. Care 2, 204-210.Berenson JR, Yellin O. New drugs in multiple myeloma. Curr Opin Support Palliat Care. 2008;2:204-10Berenson JR, Yellin O (2008) New drugs in multip...
Multiple myeloma (MM) is a malignant plasma cell disease in which tumor cells originate from plasma cells in the bone marrow, and plasma cells are cells that develop to the final stage of function of B lymphocytes. Therefore, multiple myeloma can be classified as B lymphocyte lymphoma. The ...
Some other chemotherapy drugs formultiple myelomaare: Bendamustine (Treanda) Doxorubicin (Adriamycin) Etoposide (Etopophos, Toposar, VP-16) Liposomal doxorubicin (Doxil) Other Drugs Given With Chemotherapy Some medicines help chemotherapy drugs work better. That’s also true if your cancer comes back...
Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and renal failure. In approximately 30% of cases, MM is discovered through routine blood screening when patients are...
J San-Miguel2,20, M-V Mateos3,20, B Durie17,21, JJM van Dongen5,18,21 and A Orfao1,21 Flow cytometry has become a highly valuable method to monitor minimal residual disease (MRD) and evaluate the depth of complete response (CR) in bone marrow (BM) of multiple myeloma (MM) after...
The ocular toxicity is somewhat unique for myeloma drugs. It is more of an exam finding by an ophthalmologist or an optometrist; it does not always result in significant symptoms. In fact, only in 18% to 20% of the time [does it actually result] in change in visual acuity. I think th...
摘要: The effect of immunomodulatory drugs (IMiDs) on serious infection remains uncertain. We therefore conducted a systematic review and meta-analysis to assess the possible impact of IMiDs on serious...关键词: Immunomodulatory drug Infection Multiple myeloma Systematic review Meta-analysis ...
Currently, multiple myeloma (MM) is still an incurable plasma cell malignancy in urgent need of novel therapeutic targets and drugs. Methods Bufalin was known as a highly toxic but effective anti-cancer compound. We used Bufalin as a probe to screen its potential targets by proteome microarray,...