Myeloma cells prevent bone cells from forming new bone and increase the absorption of bone already laid down, resulting in weak, thin bones characterized by holes (resembling holes in Swiss cheese) or “lytic l
How Does Multiple Myeloma Affect Your Bones? Multiple myeloma is a blood cancer that occurs when white blood cells, called plasma cells, increase out of control in the bones. Myeloma destroys the bone by making osteoclasts – cells that break down old bones – become more active and weaken yo...
X-rays: You may have x-rays to check for broken or thinning bones. An x-ray of your whole body can be done to see how many bones could be damaged by the myeloma. Biopsy: Your doctor removes tissue to look for cancer cells. A biopsy is the only sure way to know whether myeloma ...
Maintain Bone Health if You Have Multiple Myeloma Multiple myeloma can cause you to have bone pains and weak or easily broken bones. Here are ways to promote bone health. How Multiple Myeloma Affects Your Brain Multiple myeloma can have effects on your mental health and abilities. Learn how th...
EnlargeMultiple myeloma. Multiple myeloma cells are abnormal plasma cells (a type of white blood cell) that build up in the bone marrow and form tumors in many bones of the body. Normal plasma cells make antibodies to help the body fight infection and disease. As the number of multiple ...
In multiple myeloma, cancerous plasma cells multiply rapidly in the bone marrow and invade the outer layers of the bones. This can weaken bones so much that minimal trauma can cause a bone fracture at the cancer site. The myeloma plasma cells also make too much of one specific type of imm...
X-rays: You may have x-rays to check for broken or thinning bones.An x-ray of your whole body can be done to see how many bones could be damaged by the myeloma. Biopsy: Your doctor removes tissue to look for cancer cells. A biopsy is the only sure way to know whether myeloma cel...
Multiple myeloma plasma cell populations accumulate in the bone marrow, and these collections of cells called plasmacytomas can erode the hard outer shell or cortex of the bone that normally surrounds the marrow. These weakened bones show thinning of the bone, as seen in nonmalignantosteoporosisor...
Multiple myeloma was initially termed “multiple” to distinguish it from plasmacytoma, a solitary tumor of a bone or an organ/tissue. Solitary plasmacytoma (SP) may develop further into a solitary plasmacytoma with minimal marrow involvement (SPMMI). Both SP and SPMMI are characterized by monoclo...
Multiple myeloma.Pomalyst is taken along with the medicinedexamethasone, in people who: have received at least 2 prior medicines to treat multiplemyeloma, including a type of medicine known as a proteasome inhibitor andlenalidomide, and their disease has become worse during treatment or within 60 da...