Multiple system atrophyDopa-therapyDyskinesias are well-known side effects of the dopaminergic treatment in Parkinson's disease. In multiple system atrophy (MSA), these events are less well studied because of the low incidence of this disease and their relatively low frequency amongst patients ...
Multiclass classification Relevance vector machine FDG PET Parkinson's disease Multiple system atrophy Progressive supranuclear palsy Corticobasal syndrome 1. Introduction Computer-aided diagnosis (CAD) integrates data processing, mathematics and statistics into computerized techniques to maximize the information ...
however, is often unknown as a drug’s therapeutic effects are not limited to the proteins that the drug directly targets. Here, we develop the multiscale interactome, a powerful approach to explain disease treatment. We integrate
multiple-system atrophy multiplex multiplex angiosarcoma multiplex assay multiplex family multiplex polymerase chain reaction multiplication multiplicative division multiplicative growth multiplicative model multiplicity of infection multiply multipolar multipolar cell multipolar mitosis multipolar neuron multipotent multipoten...
These losses lead to impaired axonal function, increased vulnerability of axons to damage, and result in significant brain atrophy and neuro-axonal degeneration. Multiple pathomolecular processes contribute to neuroinflammation, oligodendrocyte cell death, and progressive neuronal dysfunction. In this study,...
13. Vogt IR, Lees AJ, Evert BO, Klockgether T, Bonin M, Wüllner U: Transcriptional changes in multiple system atrophy and Parkinson's disease putamen. Exp Neurol 2006, 199:465–478. doi:10.1016/j.expneurol.2006.01.008. 14. Bossers K, Wirz KTS, Meerhoff GF, Essing AHW, van Dongen ...
According to pathological score and histological analysis, the inflammation and atrophy were relieved after the addition of MLP, and the atrophic area accounted for less than 25% of the total lamina propria area (Fig. 1A and B). Compared with the control group (CN), the plasma concentration ...
Genome-wide analysis reveals MSC treatment reduces DNA single-strand breaks in aging mice To further investigate the role of MSCs in aging, we conducted a genome-wide analysis of DNA single-strand breaks called SSiNGLe, focusing on their distribution across the entire genome, exonic regions, and...
atrophy, ipsilateral ventricular enlargement, spotty calcifications, and enhancing nodules that may change in location on sequential scans. Diagnosis depends on the direct visualization of the parasite from a brain biopsy. Surgical resection of the parasite is the treatment of choice....
For the treatment of C. elegans, synchronized worms on D1 were transferred to E. coli OP50 plates with different concentrations of compounds. All worms were cultured at 25 °C. Intestinal atrophy and intestinal nuclei were observed at D7, and intestinal leakage was observed at D8. Adult ...