It is well known that complex and combined gene regulation of multi-omics is involved in the occurrence and development of breast cancer. RESULTS: In this paper, we present the Multi-Omics Breast Cancer Database (MOBCdb), a simple and easily accessible repository that integrates genomic, ...
In this paper, we present the Multi-Omics Breast Cancer Database (MOBCdb), a simple and easily accessible repository that integrates genomic, transcriptomic, epigenomic, clinical, and drug response data of different subtypes of breast cancer. 在本文中,我们介绍了多组学乳腺癌数据库(MOBCdb),这是一...
Breast cancer (BC) is a heterogeneous disease. Distinguishing BC patients with different prognosis can help to make clinical strategies. In our study, we tried to identify novel prognostic genetic biomarkers for BC by using multi-omics data and establish a risk score (RS) signature with genetic ...
Fig. 3: Molecular characterization of the multi-omics clusters. a The circular plot shows the hazard ratio (HR) of breast cancer-specific death and/or metastasis derived from a multivariate Cox regression model fitted on the set of 20 MOFs (upper), while also adjusting for age (bottom). Th...
With the advancement of high-throughput sequencing technologies, the integration of multi-omics and multi-modal data has become an important trend in the study of complex diseases. Multi-omics/multi-modal data provide new perspectives for a deeper understanding of the pathogenesis and development of ...
These findings could have implications for treating individuals with metastatic breast cancer with immune- and HER2-targeting therapies.Similar content being viewed by others The DNA methylation landscape of advanced prostate cancer Article 13 July 2020 Multi-omics analyses identify HSD17B4 methylation-...
Single-cell multi-omics technologies have emerged. They refer to the simultaneous measurement of various types of data in the same cell, allowing for an accurate and detailed depiction of the cellular state. Integrating single-cell transcriptomic sequencing with comprehensive multi-omics data to map ...
标题(英文):Prediction of axillary lymph node metastasis in triple-negative breast cancer by multi-omics analysis and an integrated model 标题(中文):基于多组学分析和整合模型的三阴性乳腺癌腋窝淋巴结转移预测 发表期刊:Ann Transl Med 作者单位:复旦大学附属肿瘤医院等 ...
Multi-omics analyses based on genes associated with oxidative stress and phospholipid metabolism revealed the intrinsic molecular characteristics of pancreatic cancer Hongdong Wang, Hui Guo, Jiaao Sun & Yuefeng Wang Scientific Reports volume 13, Article number: 13564 (2023) Cite this article 2784 Ac...
Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors Lauren M. Sanders, Rahul Chandra, Navid Zebarjadi, Holly C. Beale, A. Geoffrey Lyle, Analiz Rodriguez, Ellen Towle Kephart, Jacob Pfeil, Allison Cheney, Katr...