MDRO Page 1 of 2A multi-drug resistant organism (MDRO) is a bacteria that is resistant to many antibiotics. If bacteria are "resistant" to an antibiotic it means that certain drug treatments will not work. Examples of MDROs are: Methicillin Resistant StaphlycoccusAureus (MRSA)* Vancomycin ...
OBJECTIVE To detect and analyze the multi-drug resistant(MDR)organisms in order to rationally use the antimicrobial agents.METHODS The strains isolated from Jan to Dec 2008 were tested by ATB Expression on identification of multiple drug-resistantce and drug sensitivity test.RESULTS Among 66 Staphyloc...
We present the application of a method from robust control theory, Structured Singular Value or μ- analysis, to identify highly effective multi-drug therapies by using robustness in the face of uncertainty as a new means of target discrimination. We illustrate the method by means of a case stu...
Microbiome differential abundance analysis methods for two groups are well-established in the literature. However, many microbiome studies involve more than two groups, sometimes even ordered groups such as stages of a disease, and require different type
Epidemiological knowledge of circulating carbapenem-resistant Klebsiella pneumoniae (CRKP) is needed to develop effective strategies against this public health threat. Here we present a longitudinal analysis of 1,017 CRKP isolates recovered from patients
is a necessary step in order to ascertain whether apparent shifts in transcript levels are concordant with changes in taxon abundances. Finally, to conduct differential gene expression analysis post-normalization, off-the-shelf tools from single-organism RNA-seq can be used, some of which have alre...
Sample preparation for multi-species RNA-Seq experiments requires maximizing the number of reads from the minor organism relative to the major organism. Even when the cells of the two organisms are present in equal numbers, the RNA molecules can differ in abundance by orders of magnitude. A sing...
The resulting TK recombinant can be selected by culturing the cells in the presence of 5-bromodeoxyuridine and picking viral plaques resistant thereto. An alternative route of administration involves gene therapy or nucleic acid immunization. Thus, nucleotide sequences (and accompanying regulatory ...
While the study of the entire genetic material of an organism is known as genomics, the landscape of all the elemental genes expressed (transcripts) at a given time/condition is referred as the transcriptome. Transcripts are translated into protein molecules which may undergo further modifications to...
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