multiple‐drug‐resistant bacterial organismmultiple‐drug‐resistant Gram‐ negative rodrectal swab culturevancomycin‐resistant EnterococcusThe combination of increasing rates of antibiotic resistance and the decreasing pace of new antibiotic development has become an urgent public health crisis (1). Multiple...
Infection with multiple drug resistant (MDR) Escherichia coli poses a life threat to immunocompromised pediatric cancer patients. Our aim is to genotypically characterize the plasmids harbored in MDR E. coli isolates recovered from bacteremic patients of Children’s Cancer Hospital in Egypt 57357 (CC...
The emergence of resistant and opportunistic organisms is related to antibiotic usage and can vary significantly over time. This suggests that a policy of administering limited duration, narrow spectrum antibiotics may reduce drug resistance. 展开 ...
Members of the genus Corynebacterium are increasingly recognized as causes of opportunistic infection; some species can be multidrug resistant, posing a treatment challenge. Daptomycin is frequently used as therapy of last resort in thi... F Renaud,A Gregory,C Barreau,... 被引量: 0发表: 2013年...
This drug-resistance is one of the imperative problems to be solved in multiple myeloma patients facing a continuing struggle due to the persistence of drug-resistant tumor cells [14]. In conclusion, in order to get over the bortezomib resistance in MM, it is essential to analyze and prevent...
[62]. Superfluous mitochondria may lead to extra ATP production, which exceeds the systemic/organic energy demand and adversely affects the organism [223,224]. A classic drug for the treatment of diabetes, metformin, exerts its pharmacological effects by inhibiting mitochondrial ETC, and has been ...
the authors simultaneously evolved antimalarial drug-resistant dihydrofolate reductases in 90 replicates. 29 a.h. badran, v.m. guzov, q. huai, m.m. kemp, p. vishwanath, w. kain, a.m. nance, a. evdokimov, f. moshiri, k.h. turner,et al. continuous evolution ofbacillus thuringiensis...
(MGEs), such as plasmids, occasionally carrying multiple β-lactamases co-located with other resistance determinants, rendering these strains MDR or extensively drug-resistant (XDR)8. Australia has experienced low rates of CRE9, although sporadic introduction ofK. pneumoniaecarbapenemase (KPC)10and ...
(S. Typhimurium)13,14,15, multi-drug resistant (MDR)Klebsiella pneumoniae4orCitrobacter rodentium8,16. Members of theKlebsiella oxytocaspecies complex (KoSC), which includesK. oxytoca,KlebsiellamichiganensisandKlebsiellagrimontii17, were shown to provide CR against their more pathogenic counterparts ...
Targeting and controlled release are two key features for the design of smart drug delivery nanocarriers. The physicochemical properties of nanocarriers have significant effects on their biodistribution and clearance in vivo, including size, hydrophobicity, and charge. A living organism is a highly hetero...