The MTHFR gene mutation is a variation in the MTHFR gene that impacts your body’s ability to absorb and process folate. You inherit two copies of the MTHFR gene, one from your mother and one from your father. If you have an MTHFR gene mutation, your body may not break down folate as...
There are some things you may want to discuss with your doctor. First, if you are allergic to L-methylfolate, you should not take it. Further, you should tell your doctor if you have “seizures or epilepsy; a history of vitamin B12 deficiency or pernicious anemia; or a history of bipola...
Sound like MTHFR is important to overall health and well-being? Research now is suggesting that one in two people have an altered shape to their MTHFR gene and therefore, altered function. Should you get tested? Treatments can include taking certain B vitamins, which support the MTHFR gene pro...
et al. Treatment with 5-MTHF to support the one-carbon cycle can overcome the deleterious impact of a triple SNP mutation in the male partner’s MTHFR gene for a couple with a history of repeated miscarriage. J Assist Reprod Genet (2025). https://doi.org/10.1007/s10815-024-03371-8 ...
MTHFRSupportVariantReportv1 PreparedFor:CharlotteHorting http://.mthfrsupport SOD2rs2758331AAC+/- SOD2rs2855262TTT+/+ SOD2A16Vrs4880GAG+/- PON1Q192Rrs662CTT-/- TONGUETIE/CLEFTPALATE Gene&VariationrsID#RiskAlleleYourAlleles&ResultsNotes
Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating one-carbon metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of breast cancer in different populations. In this study, we evaluated the asso
Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population. Int J Androl. 2005;28:115–9. Article CAS PubMed Google Scholar Gupta N, Gupta S, Dama M, David A, Khanna G, Khanna A, Rajender S. Strong association of 677 C>...
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However, another polymorphism that found to be associated with venous thromboembolism risk; 4G/5G deletion/insertion polymorphism of plasminogen activator inhibitor 1 gene (PAI-1) [35], was identified as an independent risk factor for hypertension in Korean women [36]. PAI-1 is responsible for ...
We aimed to explore whether the rs2073618 variant (G1181C) of the osteoprotegerin (OPG) gene and the methylenetetrahydrofolate reductase (MTHFR) rs1801131 (A1298AC) and rs1801133 (C677T) gene polymorphisms contribute to rheumatoid arthritis (RA) suscepti