The GeneSight MTHFR test shows whether or not a person has genetic variation in MTHFR. Knowing this information could be used by a healthcare provider if they are interested in using folate supplementation as a treatment strategy for depression. The GeneSight MTHFR test shows whether or not a pe...
Understanding that the MTFHR gene impacts the way our bodies’ process toxins, and the way they function, finding a variation in the gene can help a doctor more accurately decode the underlying causes of an illness or set of symptoms. This knowledge will then help in tailoring therapies to be...
We know folate is crucial in preconception and prenatal care, so understanding whether you carry MTHFR gene polymorphisms can be a game changer in your fertility journey. I DON'T KNOW IF I HAVE MTHFR Up to 50% of people can carry changes in their MTHFR genes, which can affect fertility. ...
Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating one-carbon metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of breast cancer in different populations. In this study, we evaluated the asso
ObjectiveTo explore the role of clinical pharmacist in individualized treatment of hypertension.MethodsA patient with "H" hypertension receiving pharmaceutical care from clinical pharmacists was retrospectively analyzed.ResultsPatient's MTHFR (C677T) gene type was TT homozygous. Clinical pharmacist suggested...
and certain types of cancer. The 677C>T polymorphism in the MTHFR gene has also been suggested as a risk factor for cleft lip and palate, a birth defect in which there is a split in the upper lip and an opening in the roof of the mouth. Studies of MTHFR gene variations in people ...
Several polymorphisms of the gene encoding OPG (TNFRSF11B) mainly at promoter sites, have been associated with atherosclerosis in different patient populations; however, results from different studies are diverse13,14,15. While the RANKL/RANK/OPG system may promote RA inflammation and bone erosion,...
M. et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural–tube defects? Am J Hum Genet 62, 1044–1051 (1998). 14. Wang, L. et al. A miRNA binding site single-nucleotide polymorphism in the 3′ -UTR region of the IL23R...
Public eQTL data show that the effect of rs25487 on the expression of XRCC1 is strictly tissue dependent, showing instead for example opposite effects of the minor allele in nerve tibial cells and testis derived cells; the rs1799782 minor allele causes a minor gene ex- pression in thyroid ...
Hyperhomocysteinemia and other newly recognized inherited coagulation disorders (factor V Leiden and prothrombin gene mutation) in patients with idiopathic cerebral vein thrombosis. Cerebrovasc Dis. 2004;17(2–3):153–9. Article CAS PubMed Google Scholar Zaric BL, et al. Homocysteine and Hyperhomo...