Mechanism of action by which ajulemic acid and resveratrol modulate microglial activation in cell model of MSTull, C. ALemons, N. SSanford, T. HWight, R. DChavis, J. ADrew, P. DHensley, L. L
combining these data, such metabolomics studies may partially reveal the mechanism of action of HTH on mice. Intestinal bacteria also affect the intestinal function and immune system. Therefore, we performed 16S rDNA gene sequencing to identify intestinal bacteria associated with the response to HTH. ...
There were several scientific platform sessions devoted to MS at the meeting, concentrating on recent clinical trials (including new natalizumab data), outcomes assessment, imaging, surrogate markers and mechanism of action of current therapeutics. During the meeting, the 2005 John Dystel Prize for MS...
NC-8, an isosteviol derivative, exhibited inhibitory activity against the secretion of HBsAg and HBeAg. The action mechanism of NC-8 was distinct from those of typical HBV inhibitors. For further drug development, a bioanalytical method development, validation, and application to pharmacokinetic ...
Discussion Mechanism of action of EGB against hyperlipidemia One of the major therapeutic indications of EGB is its effects on improving central nervous system (CNS) impairments, including age-associated impairments of memory, attention and other cognitive functions[7, 28, 29]. The common pathoge-...
The results of the differential metabolite analysis showed that the use of seed kernel extracts from Xanthoceras sorbifolia treated with different methods produced similar effects on urinary metabolites in AD model mice, suggesting that the two drugs may have the same mechanism of action in AD mice...
Inhibitors of the protein dipeptidyl peptidase (DPP-IV) comprise one of the most recently licensed classes of oral antihyperglycemic drugs. These drugs differ from MEF in their mechanism of action in lowering blood glucose level, in addition they have high efficacy, low susceptibility for ...
None of the endpoints measured revealed any immunosuppressive effect of the therapeutic antibody. Activation of monocytes slightly decreased during treatment as predicted by the hypothesized mechanism of action of GNbAC1. These results support the conclusion that the antibody is safe for use in patients...
Antibacterial activity and mechanism of action of chlorogenic acid. J Food Sci. 2011;76:M398–403. Article CAS PubMed Google Scholar Hwang YJ, Lee EJ, Kim HR, Hwang KA. Molecular mechanisms of luteolin-7-O-glucoside-induced growth inhibition on human liver cancer cells: G2/M cell cycle ...
A simple mechanism to transform a monolithic Vue application into an application based on Micro Services architecture - ergonode/vuems