>Member of American Psychological Association; 30 years in clinical, counseling, and health psychology; over 10 years as director of an academic...
is made fromcannabis but has had the THC removed. In research, only cannabis preparations with a high level of THC have been found to be effective for neuropathic pain in MS in clinical trials. However, people’s anecdotal experience suggests that for some, good quality/high strength CBD oil...
In research, only cannabis preparations with a high level of THC have been found to be effective for neuropathic pain in MS in clinical trials. However, people’s anecdotal experience suggests that for some, good quality/high strength CBD oil preparations can be helpful; possibly because for ...
Although the routine monitoring of posaconazole plasma levels has not been recommended, an accurate assay could be necessary, at least in the context of clinical trials. Based on earlier toxicokinetic data, an analytical method able to measure concentrations as low as 5 μg/L is needed to accura...
(CD117).7 TND administered alone showed narrow activity in Phase I and II clinical trials in patients with myelodysplas tic syndrome and AML but, when co-administered with daunorubicin and cytarabine, it showed encouraging anti- leukemic activity in phase I/II trials in AML patients and ...
Over the past 30 years, the treatment of deep and eloquent arteriovenous malformations (AVMs) has moved away from microneurosurgical resection and towards medical management and the so-called minimally invasive techniques, such as endovascular embolizati
Clinical trials needed to examine ETX in MS patients The researchers next turned to a preclinical model in which the immune system of mice is modified to make them predisposed to MS, but the animals only develop symptoms if they are also treated with a toxin called pertussis — which also ta...
(ADME) parameters do not go for clinical trials56. Compounds satisfying Lipinski’s rule of five regarding molecular weight (≤ 500 KDa), molecular refractivity (40–130), number of H-bond donors (≤ 5), number of H-bond acceptors (≤ 10), and the octanol–water partition ...
Ocrelizumab/Ofatumumab– Should be FDA approved in 2016. Humanized form of Rituxan/Rituximab (monoclonal antibody) with positive outcomes in clinical trials. 80% decrease in relapse rate at 6 months and a 97% decrease in gadolinium enhancing lesions. In a two year time period, only 2 of 200 ...
少数感染 Epstein-Barr 病毒（如图）的人在数年后继续发展为多发性硬化。图源：Gopal Murti 博士/SPL ...