Several vaccines have been created to counteract the morbidity and mortality associated with COVID-19 and stop viral transmission, including the Moderna vaccine (Mrna-1273).The mRNA-1273 vaccine is a lipid nanoparticle-encapsulated mRNA-based vaccine that encodes the prefusion stabilized full-length ...
参考： https://www.genengnews.com/news/moderna-advancing-covid-19-vaccine-into-phase-iii-after-positive-initial-clinical-results/ 原标题：《【NEJM】mRNA-1273新冠疫苗I期临床数据正式发表！本月底将启动III期临床试验》
Open-Label, Dose-Ranging Study of the Safety and Immunogenicity of2019-nCoVVaccine(mRNA-1273) in Healthy AdultsActualStudy Start Date:March 3, 2020EstimatedPrimary Completion Date:June
The effectiveness of the mRNA-1273 vaccine against infection was negligible for the first 2 weeks after the first dose, increased to 65.5% (95% confidence interval, 62.7 to 68.0) at 14 or more days after the first dose, and ...
5. Waissengrin B, Agbarya A, Safadi E, et al. Short-term safety of the BNT162b2 mRNA COVID-19 vaccine in patients with cancer treated with immune checkpoint inhibitors. Lancet Oncol 2021;22:581-3. 6. Munro APS...
Authority]和美国国立过敏和传染病研究所[National Institute of Allergy and Infectious Diseases]资助；在ClinicalTrials.gov注册号为NCT04470427。）Lindsey R. Baden, Hana M. El Sahly, Brandon Essink, et al. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. DOI: 10.1056/NEJMoa2035389 ...
mRNA-1273 is an mRNA vaccine against SARS-CoV-2 encoding for a prefusion stabilized form of the Spike (S) protein, which was selected by Moderna in collaboration with investigators from Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID), a part ...
总而言之,该项研究进一步验证了新冠病毒疫苗mRNA-1273的抗病毒且安全的功效,同时也为开展mRNA-1273的2期和3期临床试验奠定了坚实基础。 参考资料: 1.Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates 2.美国mRNA-1273新冠疫苗Ⅰ期临床试验结果公布...
Figure1:Delayed Cutaneous Reactions to m-RNA-1273 vaccine 图表1显示的是mRNA-1273疫苗延迟皮肤反应的形态特征,包括环形斑块(患者1),均匀的抗水斑块(患者2、6和11),以及疫苗接种地点附近的靶体斑块(患者3)。在几个患者中,斑块有相当大的诱导(例如,在患者8和9中)。除了手臂局部皮疹外,还有两名患者有其他皮质...
投资者对该消息持乐观态度,截至周一上午9:19,Moderna股价在盘前交易中上涨13.5%,达到85.21美元。该股在7月14日上涨4.5%,达到75.04美元。 参考: https://www.genengnews.com/news/moderna-advancing-covid-19-vaccine-into-phase-iii-after-positive-initial-clinical-results/...