Full size image Fig. 8: Model of MRNIP condensates function in DNA damage sensing and end resection. Full size image After DSB formation, a series of DNA repair factors are recruited and concentrated at damaged DNA lesions to form DNA repair centers31. These factors form highly concentrated fo...
Full size image Further, to determine whether BLM recruitment at the DSBs depended on the enzymatic activities of MRE11 or ATM, BLM ChIP was carried out after DSB induction, in the absence or presence of either MRE11 exonuclease activity inhibitor (Mirin) or ATM kinase inhibitor (KU 55933)....
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