MRL/ lpr lupus‐prone mice show exaggerated ICAM‐1‐dependent leucocyte–endothelial interactions in response to TNF‐α. Increased leucocyte–endothelial interactions due to endothelial priming could contribute to the clinical link between infection and flares of lupus disease activity.Rheumatology...
hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stagesFengbiao Guo, Quanren Pan, Ting Chen, Shuzhen Liao, Shangmei Li, Aifen Li, Shuxian Chen, Jiaxuan Chen, Zengzhi Xiao, Hongyong Su, Lawei Yang, Chen Yang, Hua-feng Liu & Qing...
1.Objective To explore the influence of leflunomide on Janus protein-tyrosine kinase(JAK)/signal transducer and activator of transcription(STAT) signal transduction pathway in renal tissue of MRL/lpr lupus mice.目的探讨来氟米特对MRL/lpr狼疮小鼠肾脏JAK/STAT1信号转导途径的影响。 2)MRL/lpr miceMRL/...
To further define the role of the complement alternative pathway in the development of renal disease in MRL/lpr mice, we backcrossed the Df-deficient genotype onto the MRL/lpr lupus prone genetic background. As described in the Results section, serum from MRL/lpr mice deficient in Df lacked ...
学术范收录的Journal Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice,目前已有全文资源,进入学术范阅读全文,查看参考文献与引证文献,参与文献内容讨论。学术范是一个在线学术交流社区,收录论文、作者、
目的探讨来氟米特对MRL/lpr狼疮小鼠肾脏JAK/STAT1信号转导途径的影响。 2) MRL/lpr mice MRL/lpr狼疮鼠 1. Effect of arsenic trioxide on anti-dsDNA antibody and lymphocyte subsets proliferation in splenic cells of lupus-proneMRL/lpr mice; 三氧化二砷对MRL/lpr狼疮鼠抗ds-DNA抗体和脾淋巴细胞亚群增殖的影...
JAK/STAT1 Signaling Transduction Pathway in the Pathogenesis and Treatment of MRL/lpr Lupus Mice; JAK/STAT1信号转导途径在MRL/lpr狼疮鼠发病机制和治疗中的研究 2. Effects of Arsenic Trioxide on Expression of Cytokines and Lymphocyte Subsets in MRL/lpr Mice 三氧化二砷对MRL/lpr狼疮鼠淋巴细胞亚群和细...
MRL/lpr狼疮小鼠1. Objective To explore the influence of leflunomide on Janus protein-tyrosine kinase(JAK)/signal transducer and activator of transcription(STAT) signal transduction pathway in renal tissue of MRL/lpr lupus mice. 目的探讨来氟米特对MRL/lpr狼疮小鼠肾脏JAK/STAT1信号转导途径的影响。
MRL/MpJ-Fas(lpr)/J (MRL/lpr) mice represent a well-established mouse model of human systemic lupus erythematosus. MRL/lpr mice homozygous for the spontaneous lymphoproliferation mutation (lpr) are characterized by systemic autoimmunity, massive lymphadenopathy associated with proliferation of aberrant T...
FK506: therapeutic effects on lupus dermatoses in autoimmune-prone MRL/Mp-lrp/lrp mice. Arch Dermatol Res 1995;287:558-63.Furukawa F, Imamura S, Takigawa M (1995) FK 506: therapeutic effects on lupus dermatoses in autoimmune-prone MRL/MP-lpr mice. Arch Dermatol Res 287:558-563...