检测多发性骨髓瘤患者MRD,NGS、NGF、PET-CT哪家强? 在中国免疫及靶向治疗高峰论坛暨高博第三届淋巴瘤&骨髓瘤国际高峰论坛上,MAYO CLINIC陈东、Min Shi教授分享了题为“Myeloma MRD Testing”的精彩报告,和与会专家分享骨髓瘤微小残留病...
[5]. Johnson, J. Janssen Announces DARZALEX® (daratumumab) U.S. FDA Approval for Newly Diagnosed Patients with Multiple Myeloma who are Transplant Ineligible. 2018; Available from: https://www.jnj.com/media-center/press-relea...
EP: 4.MRD Testing in Multiple Myeloma EP: 5.Managing Adequate/Inadequate Treatment Response in MM EP: 6.Managing A Case of Newly-Diagnosed Transplant-Ineligible MM EP: 7.Triplet Vs Doublet Therapy for Transplant-Ineligible MM EP: 8.Maintenance Therapy for Transplant-Ineligible MM ...
参考文献:Costa, L.J., Medvedova, E., Dhakal, B. et al. Implications of isolated MRD progression in newly diagnosed multiple myeloma treated with quadruplet therapy. Blood Cancer J. 15, 13 (2025). https://doi.org/10.1038/s41408-025-01219-7. 艾沐蒽专注于免疫组二代测序领域多年,是全国首...
Hans Lee, MD, explores how minimal residual disease (MRD) testing guides treatment decisions for multiple myeloma and highlights the value of patient preferences.
0:47 |What we do not know is if MRD alone is sufficient to decide on discontinuation of therapy, or should we monitor additional parameters in addition to the regular myeloma labs that we measure? If so, how frequently should we measure that, especially when we decide to take patients off...
Using modern combination therapy in newly diagnosed multiple myeloma patients, high proportions of newly diagnosed multiple myeloma patients obtain minimal residual disease (MRD) negativity and MRD testing has rapidly become an integral part of clinical trials focusing on patients in this setting. Only ...
EP: 10.MRD Negativity in Multiple Myeloma EP: 11.The Value of MRD Testing in Lymphoid Malignancies Newsletter Stay up to date on the most recent and practice-changing oncology data Subscribe Now! Latest CMEView AllVideo Community Oncology Connections™: Community Oncologists’ Role in Selecting ...
Thomas Martin, MD:Yes, so we’ve been using next-generation sequencing for MRD testing for quite a long time now. We also send samples to the Mayo Clinic for EuroFlow. So we’ve had experience with both. I will say that for us MRD negativity is 10 to the minus 6. I still think ...
MRD testing in multiple myeloma: the main future driver for modern tailored treatment. Semin Hematol. 2018;55:44–50. Article PubMed Google Scholar Berger N, Kim-Schulze S, Parekh S. Minimal residual disease in multiple myeloma: impact on response assessment, prognosis and tumor heterogeneity....