Mouse allergen exposure, wheeze and atopy in the first seven years of life Top of pageMethods Results Discussion Acknowledgments References Background: Little is known about mouse allergen exposure in home environments and the de... W Phipatanakul,JC Celedon,CD Ramsey,... - 《Allergy》 被引量...
Mice have been used in biomedical research for hundreds of years. As a result of long usage, many techniques have been developed to dose and evaluate mice, and a wealth of historical data has been accumulated in the literature. A wide variety of genetic strains have been developed for ...
Genetically modified mice have been studied for more than fifteen years asmodels of cystic fibrosis (CF). The large amount of experimental data generated i... BJ Scholte,MC Erasmus 被引量: 21发表: 0年 Characterisation of lung disease in mouse models of cystic fibrosis Firstly, this thesis des...
The human phenome project. Nat. Genet. 34, 15–21 (2003). References 43–46 illustrate the worldwide ongoing efforts in various aspects of phenomics. CAS PubMed Google Scholar Jones, A. R., Overly, C. C. & Sunkin, S. M. The Allen Brain Atlas: 5 years and beyond. Nat. Rev. ...
human35,36and mouse37,38cortexin vivosupporting the physiological relevance of our findings. BDE-99 reduced differentiated O4+cells/nuclei of both species concentration-dependently after 5 days without reducing viability (Fig. 1A,C). Human O4+cell formation was found to be 7 times more sensitive...
The application of electron microscopy to the functional morphology of the anterior pituitary since more than thirty years ago led us to the well known hyp... K Kurosumi 被引量: 20发表: 1986年 Identification by plaque assays of a pituitary cell type that secretes both growth hormone and prola...
Part mouse, part human "Our goal was to have amouse modelthat would allow us to study the disorder and test potential treatments," said co-first author Dr. Beatrice Bissig-Choisat, assistant professor at Duke University. "Applying our lab's yearslong expertise developing chimeric mouse models...
Since its discovery 30 years ago, Sry has been believed to be a single-exon gene. Here, ... S Miyawaki,S Kuroki,R Maeda,... - 《Science》 被引量: 0发表: 0年 Clinical and anatomical spectrum in XX sex reversed patients. Relationship to the presence of Y specific DNA-sequences ...
(low oestrogen-high progesterone)14, reminiscent of the human follicular and luteal phase, respectively (Fig.1a). From all three groups, vHIP tissue was first cross-linked to ‘fix’ protein to DNA and preserve 3D interactions, nuclei were isolated, and neuronal (NeuN+) nuclei were purified ...
Nevertheless, the physiological OLG turnover seems to be quite low, both in mice and humans23,24. The generation of new myelin sheaths has been recently observed from mature OLG using in vivo two-photon imaging25. Twenty years ago, Bergles and Jahr26 discovered the presence of functional ...