We compared 18 human and mouse tissues, and found 9 significantly correlated tissue pairs. Functional analysis also revealed some terms related to aging in human and mouse. And we performed a crosswise comparison of homologous age-related genes with 18 tissues in human and mouse respectively, and...
COMPARISON OF THE STRUCTURE OF HUMAN AND MOUSE LYMPHOID MICROENVIRONMENTS In terms of anatomy, the gastrointestinal tract is similar in both mice and humans. There are three distinct mucosal lymphoid microenvironments: first, the mucosa-associated lymphoid tissue (MALT); second, the diffuse connective...
To address these gaps in knowledge, we perform an integrative analysis of resting and inflamed leukocytes from humans and mice and assess the degree of conservation of gene expression. We find that human and mouse transcriptomes can be analyzed together and that lineage-specific gene expression was ...
Translational Medicine Communications (2023) 8:9 https://doi.org/10.1186/s41231-023-00139-7 Translational Medicine Communications RESEARCH Open Access Comparison of gene expression between human and mouse iPSC‑derived cardiomyocytes for stem cell therapies of cardiovascular defects via ...
International Journal of Human-Computer Interaction, 26(7), 703-734.Hertzum, M., & Hornbaek, K. (2010). How age affects pointing with mouse and touchpad: A comparison of young adult, and elderly users. International Journal of Human-Computer Interaction, 26, 703-734. doi:10.1080/...
Evidence that the species barrier of human immunodeficiency virus-1 does not extend to uptake by the blood--brain barrier: comparison of mouse and human br... HIV-1 within the CNS produces a neuroAIDS syndrome and may act as a reservoir for reinfection of the peripheral tissues. Study of ...
(McCarthy et al., 2014; El-Maarri et al., 2007; Mamrut et al., 2015), and show that despite the aforementioned studies which used young to middle-age human tissue, these sex-differences can be found within the dorsal hippocampus of aging mice specifically and can be stable across the...
Comparison of these mice showed that BDNF modulates competition in axonal branching33, which may be involved in Met66 allele-associated neurological dysfunction. Humanisation in this case, while providing a useful model to study human variation, was not critical since others have created a BDNF ...
Human and mouse DCs can be divided into several subtypes on the basis of surface antigen differences. Many DC subtypes respond differently to microbial products, produce different cytokines and regulate the responses of the T cells they activate. DC subtypes differ in their functional potential bu...
1.A transgenic mouse or living part thereof comprising a chimeric APP gene encoding a human Aβ having a FAD mutation and differing from the human APP gene of SEQ ID NO: 1 in that the Ile at amino acid 716 in the human APP gene of SEQ ID NO: 1 is substituted with an amino acid ...